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Comprehensive genetic study provides new insights on cleft lip and palate


Comprehensive genetic study provides new insights on cleft lip and palate
Cleft lip and palate is one of the most common congenital malformations. Its causes are mainly genetic. However, it is still largely unknown exactly which genes are affected. A new international study led by the University of Bonn now provides new insights. The results are published in the journal
Human Genetics and Genomics Advances, but are already available online.
The researchers from the Institute of Human Genetics at the University Hospital Bonn combined various data sources in their work. In the course of their research, they discovered five new regions in the human genome in which variations in the DNA sequence are associated with an increased risk of malformation. A total of 45 such risk regions are now known. For some of them, the researchers were also able to show which genes are affected by these changes. Our results provide new insights into the development of the disease, but also ....

Nordrhein Westfalen , United States , Julia Welzenbach , Kerstin Ludwig , Emmy Noether , Emily Henderson , Bonn University Hospital , Johns Hopkins University In Baltimore , Institute Of Human Genetics , University Hospital Bonn , University Of Cantabria , Emory University In Atlanta , German Research Foundation , University Of Bonn , Human Genetics , Genomics Advances , Johns Hopkins University , Emory University , னோற்ர்ேன் வெஸ்ட்ஃபாலன் , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , பொன் பல்கலைக்கழகம் மருத்துவமனை , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் இல் பால்டிமோர் , நிறுவனம் ஆஃப் மனிதன் ஜெநெடிக்ஸ் , பல்கலைக்கழகம் மருத்துவமனை பொன் , பல்கலைக்கழகம் ஆஃப் கான்டாப்ரியா ,

Innovative corona test offers great potential for systematic testing


Innovative corona test offers great potential for systematic testing
A new corona test developed at the University Hospital Bonn can analyze a large number of swabs simultaneously using sequencing technology and has a similarly high sensitivity as the common qPCR test. The innovative method offers great potential, especially for systematic testing in daycare centers, schools or companies. Today, the results of the study on the new Corona test have been published in the renowned journal
Nature Biotechnology .
In addition to vaccination, systematic testing of the population remains of central importance in order to effectively monitor and contain the spread of infections during the Coronavirus pandemic. Only in this way can the spread of the virus be effectively monitored and contained through targeted measures. ....

Nordrhein Westfalen , Wolfgang Holzgreve , Bundesweites Forschungsnetz Angewandte , Kerstin Ludwig , Emily Henderson , Jonathan Schmid Burgk , Broad Institute , German Federal Ministry Of Education , Institute Of Human Genetics , University Hospital Bonn , Public Health , University Of Bonn , Institute Of Clinical Chemistry , Institute Of Hygiene , Clinical Chemistry , Clinical Pharmacology , Life Brain Gmbh , Bundeswehr Central Hospital Koblenz , Medical Director , German Federal Ministry , Forschungsnetz Angewandte Surveillance , னோற்ர்ேன் வெஸ்ட்ஃபாலன் , எமிலி ஹென்டர்சன் , ஜொனாதன் ஸ்கிமிட் பர்க் , பரந்த நிறுவனம் , ஜெர்மன் கூட்டாட்சியின் அமைச்சகம் ஆஃப் கல்வி ,