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Worldwide network develops SARS-CoV-2 protocols for research laboratories


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IMAGE: Scientists Martin Hengesbach (left) und Andreas Schlundt at the nuclear magnetic resonance (NMR) spectrometre at Goethe-University Frankfurt, Germany.
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Credit: Uwe Dettmar for Goethe-University Frankfurt, Germany
FRANKFURT. When the SARS-CoV-2 virus mutates, this initially only means that there is a change in its genetic blueprint. The mutation may lead, for example, to an amino acid being exchanged at a particular site in a viral protein. In order to quickly assess the effect of this change, a three-dimensional image of the viral protein is extremely helpful. This is because it shows whether the switch in amino acid has consequences for the function of the protein - or for the interaction with a potential drug or antibody. ....

Rio Preto , Santa Catarina , Switzerland General , United States , Frankfurt Am Main , Duque De Caxias , Estado Do Rio , Sesto Fiorentino , Baden Wüberg , Rio De Janeiro , Andreas Schlundt , Halle Saale , Martin Hengesbach , Harald Schwalbe , Charles Tanford Protein Centre , Lyon University , Chemical Biology At Goethe University , Institute Of Organic Chemistry , University Of Rio De Janeiro , Goethe Coronavirus Fund , Institute For Molecular Virology , University Of Florence , Oswaldo Cruz Foundation , Spanish National Research Council , Institute For Biochemistry , Institute Of Medical Biochemistry ,

DNA from Pleistocene Era Mammoth Lineages Elucidated | McDonnell Boehnen Hulbert & Berghoff LLP


T
he wooly mammoth (
Mammuthus primigenius) is an iconic animal, like the saber tooth tiger or dire wolf, from a time in human history when our position at the top of the global food chain was decidedly not assured (and being something s prey was not limited to just other humans). Perhaps this is a reason that resurrection of mammoths using Jurassic Park-like technology has some currency and appeal (
but see
How to Clone a Mammoth for reasons why this may not be such a good idea). Perhaps paradoxically, the mammoth arose in Africa 5 million years ago and like its (very) distant ....

Sakha Yakutiya , United States , United Kingdom , Uppsala Lan , City Of , Orenburgskaya Oblast , Wikimedia Commons , America Mammuthus , Thomas Quine , Department Of Ecology , Uppsala University , University Of Copenhagen , Russian Academy Of Sciences , Science For Life Laboratory , Stockholm University , Department Of Archaeology , Technical University , Natural History Museum , China Agricultural University , Department Of Cell , Department Of Biomolecular Engineering , Centre For Palaeogenetics , University Of California Santa Cruz , College Of Plant Protection , University Of Potsdam , Institute For Biochemistry ,