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Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays


Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays
A joint research group from KAIST and Institut Pasteur Korea has identified repurposed drugs for COVID-19 treatment through virtual screening and cell-based assays. The research team suggested the strategy for virtual screening with greatly reduced false positives by incorporating pre-docking filtering based on shape similarity and post-docking filtering based on interaction similarity. This strategy will help develop therapeutic medications for COVID-19 and other antiviral diseases more rapidly. This study was reported at the
Proceedings of the National Academy of Sciences of the United States of America (PNAS).
Researchers screened 6,218 drugs from a collection of FDA-approved drugs or those under clinical trial and identified 38 potential repurposed drugs for COVID-19 with this strategy. Among them, seven compounds inhibited SARS-CoV-2 replication in Vero cells. Three ....

United States , Dae Jang , Emily Henderson , Institut Pasteur Korea , National Academy , Distinguished Professor Sang Yup , ஒன்றுபட்டது மாநிலங்களில் , டே ஜங் , எமிலி ஹென்டர்சன் , நிறுவனம் பாஸ்டர் கொரியா , தேசிய கலைக்கழகம் , புகழ்பெற்ற ப்ரொஃபெஸர் பாடினார் ஆம் ,

Identifying how chemotherapy drug works could deliver personalized cancer treatment

Identifying how chemotherapy drug works could deliver personalized cancer treatment
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Gyoosik Kim , Yongsuk Ku , Department Of Chemical , National Academies , Biomolecular Engineering , Institut Pasteur Korea , துறை ஆஃப் இரசாயன , உயிர் மூலக்கூறு பொறியியல் , நிறுவனம் பாஸ்டர் கொரியா ,