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New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates

New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates
Frontline staff at Norfolk and Norwich University Hospitals (NNUH) are among the first in the country to benefit from the rollout of more accurate saliva tests in a bid to curb Covid transmission rates.
Combined with the vaccination programme, these rapid tests should help to significantly reduce the ability of the virus to spread in healthcare settings.
In partnership with the Norfolk and Norwich Pathology Lab, the Earlham Institute (EI) and the Eastern Pathology Alliance, the Government-commissioned programme introduces a new, more reliable COVID testing programme for frontline workers. ....

Ngozi Elumogo , Richard Goodwin , Karim Gharbi , Neil Hall , Emily Henderson , Norwich Research Park , Norwich Pathology Lab , Eastern Pathology Alliance , Consultant Microbiologist Lab Medicine Clinical , Norwich University Hospitals , Waveney Health Partnership , Earlham Institute , Clinical Support Services , Norwich Research , Genomics Pipelines , Clinical Lead , Covid Testing , Pathology Incident Director , Consultant Microbiologist , Lab Medicine Clinical Director , Health Care , ரிச்சர்ட் குட்வின் , நீல் மண்டபம் , எமிலி ஹென்டர்சன் , நார்விச் ஆராய்ச்சி பூங்கா , நார்விச் நோயியல் ஆய்வகம் ,

Researchers probe deeper into the neuronal mechanisms underlying olfactory dysfunction in Alzheimer's

Researchers probe deeper into the neuronal mechanisms underlying olfactory dysfunction in Alzheimer’s
Loss of smell or olfactory dysfunction is an early indication of the neurodegenerative Alzheimer s disease (AD) and appears in approximately 90% of all patients. While loss of smell is a major symptom, patients with AD are only unable to recognize specific odors and do not completely lose their sense of smell; this suggests a possible region-specific involvement of the olfactive center in the brain.
Amyloid β (Aβ), a toxic protein that accumulates in the brain is a known contributing factor in AD pathogenesis and is also present in the olfactory system that controls the sense of smell. However, the pathology and mechanisms of AD-specific olfactory dysfunction involving olfactory sensory neurons (OSNs) remain unclear. ....

Emily Henderson , Alzheimer Research , Professor Cheil Moon , Alzheimer 39s Disease , Mouse Model , எமிலி ஹென்டர்சன் , முதுமறதி ஆராய்ச்சி , சுட்டி மாதிரி ,

Study explains the evolution of SARS-CoV-2 virus

Study explains the evolution of SARS-CoV-2 virus
As COVID-19 sweeps the world, related viruses quietly circulate among wild animals. A new study shows how SARS-CoV-2, the virus that causes COVID-19, and SARS-CoV-1, which caused the 2003 SARS outbreak, are related to each other.
The work, published recently in the journal
Virus Evolution, helps scientists better understand the evolution of these viruses, how they acquired the ability to infect humans and which other viruses may be poised for human spillover.
How did these viruses come to be what they are today? Why do some of them have the ability to infect humans while others do not? ....

United States , Heather Wells , Simon Anthony , Emily Henderson , University Of California , School Of Veterinary Medicine , Columbia University , Virus Evolution , Study Senior Author , Associate Professor , Veterinary Medicine , Sars Cov 2 , ஒன்றுபட்டது மாநிலங்களில் , ஹீத்தர் கிணறுகள் , சிமோன் அந்தோணி , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , பள்ளி ஆஃப் கால்நடை மருந்து , கொலம்பியா பல்கலைக்கழகம் , வைரஸ் பரிணாமம் , படிப்பு மூத்தவர் நூலாசிரியர் , இணை ப்ரொஃபெஸர் , கால்நடை மருந்து ,

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. To date, SARS-CoV-2 has infected over 112 million people and has been responsible for over 2.48 million deaths.
While vaccines against SARS-CoV-2 are being administered globally, treatment options for those infected are still limited. A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.
The researchers demonstrated PT150 as an effective inhibitor of SARS-CoV-2 infection in the Syrian golden hamster model. They found that oral PT150 given once daily for seven days prevented replication of SARS-CoV-2 in the lungs, decreased infiltration of macrophages, improved lu ....

Ramya Dwivedi , Syrian Hamster , Antiviral Drug , Coronavirus Disease Covid 19 , In Vivo , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Corona Virus , Immune Response , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ரம்யா டுவிவேடி , சிரிய வெள்ளெலி , இல் விவோ , கொரோனா வைரஸ் , நோய் எதிர்ப்பு சக்தி பதில் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Basic cell health systems wear down in Huntington's disease, analysis shows

Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found. ....

Myriam Heiman , Mary Wertz , Christian Neri , Barbara Gris , Thomas Vogt , Jasmin Cevost , Lucile Megret , Jeff Aaronson , Satish Nair , Jim Rosinski , William Yang , Hilary Wilkinson , Broad Institute , University Of California At Los Angeles , Department Of Brain , National Institutes Of Health , Cognitive Sciences , Picower Institute For , Sorbonne Centre National De La Recherche Scientifique , Sorbonne Universit , Picower Institute , Centre National De La Recherche Scientifique , Los Angeles , National Institutes , University Of California , Immune Response ,