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A link between childhood stress and early molars


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Early in her career neuroscientist Allyson Mackey began thinking about molars. As a researcher who studies brain development, she wanted to know whether when these teeth arrived might indicate early maturation in children.
I ve long been concerned that if kids grow up too fast, their brains will mature too fast and will lose plasticity at an earlier age. Then they ll go into school and have trouble learning at the same rate as their peers, says Mackey, an assistant professor in the Department of Psychology at Penn. Of course, not every kid who experiences stress or [is] low income will show this pattern of accelerated development. ....

University Of Pennsylvania , United States , Penn School , Cassidy Mcdermott , Joanna Scott , Austin Boroshok , Erin Bumann , Ursula Tooley , Katherine Hilton , Allyson Mackey , Muralidhar Mupparapu , School Of Arts Sciences At Penn , Department Of Psychology , Department Of Psychology At Penn , National Health , National Science Foundation , University Of Missouri , Penn School Of Dental Medicine , Nutrition Examination Survey , Brain Lab , National Institute On Drug Abuse Grant , Department Of Oral Medicine , Jacobs Foundation , School Of Dentistry , Proceedings Of The National Academy Sciences , School Of Arts Sciences ,

To combat gum disease, help oral bacteria evolve


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Tsukuba, Japan Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut. Bacteria that cause inflammation in the mouth are transported through the digestive tract to the gut and liver, where they can cause liver inflammation. Lipopolysaccharides, important structural molecules in some bacteria, act as endotoxins, producing systemic effects that can manifest as non-alcoholic fatty liver disease (NAFLD). Now, a multidisciplinary team from the University of Tsukuba show that exercise could be used to improve the oral environment in people with NAFLD, potentially leading to a new treatment for the disease. ....

Junichi Shoda , Public Health , International Journal Of Environmental Research , University Of Tsukuba , Professor Junichi , Oral Microbiota , Alcoholic Fatty Liver Disease , International Journal , Environmental Research , Medicine Health , Dentistry Periodontal Disease , Diet Body Weight , Metabolism Metabolic Diseases , பொது ஆரோக்கியம் , சர்வதேச இதழ் ஆஃப் சுற்றுச்சூழல் ஆராய்ச்சி , பல்கலைக்கழகம் ஆஃப் ட்சூகுபா , ஆல்கஹால் கொழுப்பு கல்லீரல் நோய் , சர்வதேச இதழ் , சுற்றுச்சூழல் ஆராய்ச்சி , உயிர் வேதியியல் , மருந்து ஆரோக்கியம் , பல் மருத்துவம் பெரியடாஂடல் நோய் , உணவு உடல் எடை , வளர்சிதை மாற்றம் வளர்சிதை மாற்ற நோய்கள் ,

Imbalance in gum bacteria linked to Alzheimer's disease biomarker


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Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta a key biomarker for Alzheimer s disease in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer s biomarker called tau.
The study, published in the journal
Alzheimer s & Dementia: Diagnosis, Assessment & Disease Monitoring, adds to the growing evidence of a connection between periodontal disease (gum disease) and Alzheimer s. Periodontal disease which affects 70 percent of adults 65 and older, according to CDC estimates is characterized by chronic and systemic inflammation, with pockets between the teeth and gums enlarging and harboring bacteria. ....

Karlav Ballman , Kaj Blennow , Henrik Zetterberg , Deepthi Gulivindala , Angela Kamer , Smruti Pushalkar , Lidia Glodzik , Patricia Corby , Kumar Raghava Chowdary , Deepak Saxena , Tracy Butler , University Of Pennsylvania School Dental Medicine , National Center , College Of Dentistry , Translational Sciences , University Of Gothenburg , Sahlgrenska University , Alzheimer Association , Craniofacial Research , Weill Cornell , Disease Monitoring , Brain Health Imaging Institute , Kumar Raghava Chowdary Annam , Weill Cornell Medicine , Pennsylvania School , Dental Medicine ,

Certain mouthwashes might stop COVID-19 virus transmission


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Researchers at Rutgers School of Dental Medicine have found evidence that two types of mouthwash disrupt the COVID-19 virus under laboratory conditions, preventing it from replicating in a human cell.
The study, published in the journal
Pathogens, found that Listerine and the prescription mouthwash Chlorhexidine disrupted the virus within seconds after being diluted to concentrations that would mimic actual use. Further studies are needed to test real-life efficacy in humans.
The study was conducted in a lab using concentrations of the mouthwash and the time it would take to contact tissues to replicate conditions found in the mouth, said Daniel H. Fine, the paper s senior author and chair of the school s Department of Oral Biology. ....

Eileen Hoskin , Kenneth Markowitz , Chuan Xu , Theresa Chang , Researchers At Rutgers School Of Dental Medicine , Public Health Research Institute , Rutgers School Of Dental Medicine , Rutgers New Jersey Medical School , Department Of Oral Biology , Rutgers School , Dental Medicine , Public Health Research , Carla Cugini , Medicine Health , Dentistry Periodontal Disease , Infectious Emerging Diseases , ஐலீந் ஹோஸ்கின் , கெநெத் மார்க்கோவிட்ஸ் , சுவான் ஐயூ , தெரேசா சாங் , ஆராய்ச்சியாளர்கள் இல் ரட்ஜர்ஸ் பள்ளி ஆஃப் டெஂடல் மருந்து , பொது ஆரோக்கியம் ஆராய்ச்சி நிறுவனம் , ரட்ஜர்ஸ் பள்ளி ஆஃப் டெஂடல் மருந்து , ரட்ஜர்ஸ் புதியது ஜெர்சி மருத்துவ பள்ளி , துறை ஆஃப் வாய்வழி உயிரியல் , ரட்ஜர்ஸ் பள்ளி ,

HKUST researchers unlock the micro-molecular physiochemical mechanism of dental plaque formation


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IMAGE: (Left up panel) Effect of biosynthetic gene cluster muf or mutanofactin-697 (5) on biofilm formation on the surface of artificial acryl teeth. (Left bottom panel) Proposed biosynthetic pathway for mutanofactin-697.
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Credit: HKUST
An inter-disciplinary team of researchers led by Prof. Qian Peiyuan, Chair Professor at the Hong Kong University of Science and Technology (HKUST) s Department of Ocean Science and Division of Life Science has unraveled how a novel microbial small molecule released by Streptococcus mutans (S. mutans) - a bacterium commonly found in the human oral cavity - is connected to dental caries development using a synthetic biology approach, offering new insights to the health impact of the human oral microbiota and facilitating future research on the prevention of tooth decay. The research findings were recently published in the prestigious scientific journal ....

Hong Kong , Qian Peiyuan , Division Of Life Science , College Of Dentistry , Department Of Ocean Science , National Institutes Of Health , University Of California At Berkeley , University Of Florida , Hong Kong University Of Science , Chair Professor , Hong Kong University , Ocean Science , Life Science , Nature Chemical Biology , National Institutes , Hansemann Professor , Molecular Biology , Dentistry Periodontal Disease , ஹாங் காங் , பிரிவு ஆஃப் வாழ்க்கை அறிவியல் , கல்லூரி ஆஃப் பல் மருத்துவம் , துறை ஆஃப் கடல் அறிவியல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா இல் பெர்க்லி , பல்கலைக்கழகம் ஆஃப் புளோரிடா , ஹாங் காங் பல்கலைக்கழகம் ஆஃப் அறிவியல் ,