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Experimental drug that boosts immunotherapy reveals promise in bladder cancer study

Experimental drug that boosts immunotherapy reveals promise in bladder cancer study
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United States , North Carolina , Matthewi Milowsky , Ujjawal Manocha , Seant Bailey , Wolfgang Beck , Andrews Truong , Charlesm Perou , Takanobu Utsumi , Mi Zhou , Bhavani Krishnan , Lineberger Williamy Kim , Sarae Wobker , Lineberger Tracy Rose , Kyleg Stewart , Christofc Smith , Lisam Bixby , Lineberger Benjamin Vincent , School Of Medicine , Career Development Award In Clinical Oncology , University Cancer Research Fund To Kim , Doris Duke Charitable Foundation , Uhera Foundation To Utsumi , American Cancer Society , Distinguished Professor , Benjamin Vincent ,

Advanced Chemotherapy Technologies, Inc. Awarded $4 Million NIH Grant to Pursue Treatment for Locally Advanced Non-resectable Pancreatic Cancer

Advanced Chemotherapy Technologies, Inc. Awarded $4 Million NIH Grant to Pursue Treatment for Locally Advanced Non-resectable Pancreatic Cancer
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Cancer Drug Shows Potential Against Pseudo SARS-CoV-2 in Lab Tests

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Cancer Drug Shows Potential Against Pseudo SARS-CoV-2 in Lab Tests
Despite the effectiveness of COVID-19 vaccines, treatments are still needed to combat this disease, which has killed millions of people and still kills thousands each day across the world. Scientists at the UNC School of Medicine conducted lab experiments showing how the cancer drug lenalidomide disrupts a cellular pathway in human cells so that pseudo-viruses derived from SARS-CoV-2 – the virus that causes COVID-19 – cannot enter cells to cause infection.
The research, published in a letter to the journal Signal Transduction and Targeted Therapy, shows the potential of an existing FDA-approved drug to help doctors treat the sickest COVID-19 patients. ....

United States , Siyuan Su , Pengda Liu , Lilly Wong , Guochun Jiang , Ying Wang , Jianfeng Chen , School Of Medicine , Guochun Jiang Lab , Breast Cancer Alliance Young Investigator Grant , Department Of Biochemistry , University Cancer Research Fund , Pengda Liu Lab , Lineberger Comprehensive Cancer Center , Gabrielle Angel Foundation Medical Research Award , Cure Center , V Scholar Research Grant , Signal Transduction , Targeted Therapy , Comprehensive Cancer Center , Angel Foundation Medical Research Award , Cancer Research , Qura Therapeutics , North Carolina , Chapel Hill Center , ஒன்றுபட்டது மாநிலங்களில் ,

Engineered safety switch curbs severe side effects of CAR-T immunotherapy

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IMAGE: Matthew Foster, MD, and his UNC Lineberger colleagues have used an experimental safety switch incorporated as part of a chimeric antigen receptor-modified T cell therapy (CAR-T) for an aggressive form.
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Credit: UNC Lineberger Comprehensive Cancer Center
CHAPEL HILL, North Carolina UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur. This advance was seen in a patient enrolled in a clinical trial using CAR-T to treat refractory acute B-cell leukemia. It demonstrates a proof-of-principle for possible expanded use of CAR-T immunotherapy paired with the safety switch. ....

Winnie Lau , Natalie Grover , Robert Hagan , Anastasia Ivanova , Brianne Buchanan , Matthew Foster , Daiichi Sankyo , Kaitlin Morrison , Catherine Cheng , James Coghill , Spencer Laing , Aaron Foster , Paul Armistead , John West , Barbara Savoldo , Jonathan Serody , Lineberger Cellular Immunotherapy Program , Gillings School Of Global Public Health , School Of Medicine , Bellicum Pharmaceuticals , Marsico Lung Institute , University Cancer Research Fund , Merck Inc , Advisory Board Of Kite Pharmaceuticals , Cellular Immunotherapy Program , Lineberger Comprehensive Cancer Center ,

Advanced Chemotherapy Lands $2.5M Investment From Spectrum Financial | North Carolina Biotechnology Center

Advanced Chemotherapy Technologies (ACT), a medical device startup developing a way to improve the treatment of pancreatic cancer, has added $2.5 million in funding to support clinical testing of its technology.
ACT device, code-named ACT-IOP-003.
ACT photos
The technology of Raleigh-based ACT is a drug delivery system. The device, code-named ACT-IOP-003, is about the size of a quarter. Implanted in the pancreas, it employs a technique called iontophoresis, which involves running a mild electric current. That current drives gemcitabine, a type of chemotherapy, into the tumor. This approach is intended to be a more targeted way of delivering a drug to the spot where it’s needed. ....

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