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4) for a multiple sequence alignment (
5) with the new sequences and 127 publicly available B.1.1.7 genomes from around the world available on GISAID (
6) as of December 31, 2020 (https://github.com/CADDE-CENTRE/VOC-Lineage-Brazil). The virus genome recovered from patient 1 grouped within a well-supported cluster (bootstrap 85%) of 10 sequences (60% from the United Kingdom) (Figure). This finding is consistent with the travel history of an asymptomatic family member who was positive for SARS-CoV-2 (according to a rapid test performed on December 23, 2020), who arrived in São Paulo on December 17 after traveling from Italy to the United Kingdom and, after a short stay, from London to São Paulo, and who was in close contact with patient 1. The sequence from patient 2 clustered with good statistical support (bootstrap 79.4%) with a sequence collected in the United Kingdom on November 27. Patient 2 had traveled from London to São Paulo on December 19 and was symptomatic whe ....

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