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New algorithm could help enable next-generation deep brain stimulation devices


New algorithm could help enable next-generation deep brain stimulation devices
Brown University researchers have developed a technique that could allow deep brain stimulation devices to sense activity in the brain and adjust stimulation accordingly.
PROVIDENCE, R.I. [Brown University] By delivering small electrical pulses directly to the brain, deep brain stimulation (DBS) can ease tremors associated with Parkinson’s disease or help relieve chronic pain. The technique works well for many patients, but researchers would like to make DBS devices that are a little smarter by adding the capability to sense activity in the brain and adapt stimulation accordingly.
Now, a new algorithm developed by Brown University bioengineers could be an important step toward such adaptive DBS. The algorithm removes a key hurdle that makes it difficult for DBS systems to sense brain signals while simultaneously delivering stimulation.    ....

Jonathan Calvert , Anusha Allawala , Nithya Ramakrishnan , Kelly Bijanki , Sohail Syed , David Borton , Evan Dastin Van Rijn , Michelle Avendano Ortega , Evan Matteson , Roee Gilron , Nicole Provenza , Radu Darie , Philip Starr , Gregory Vogt , Matthew Harrison , Denise Oswalt , Sameer Sheth , Wayne Goodman , Defense Advanced Research Projects Agency , University Of Minnesota , Brown University , Brown Carney Institute For Brain Science , National Institutes Of Health Brain Initiative , National Institute Of Neurological Disorders , Cell Reports , Carney Institute ,

Brain Wave Recordings Reveal Potential for Individualized Parkinson's Treatments


Date Time
Brain Wave Recordings Reveal Potential for Individualized Parkinson’s Treatments
Pioneering neural recordings in patients with Parkinson’s disease by UC San Francisco scientists are providing the groundwork for personalized brain stimulation to treat Parkinson’s and other neurological disorders.
In a study published May 3 in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many months, with and without deep brain stimulation (DBS) therapy. Pairing the brain recordings with wearable monitors of movement, they identified patterns of brain activity corresponding to specific movement abnormalities associated with Parkinson’s. Their research provides the first evidence, during normal activities of daily living, for a long-held hypothesis that Parkinson’s symptoms are related to erratic brain wave patterns, and demonstrate how DBS restores order to patient bra ....

United States , Roee Gilron , Philip Starr , Philipa Starr , Parkinson Foundation , Medtronic Inc , Department Of Neurological Surgery , Weill Institute For Neurosciences , Nature Biotechnology , Dolores Cakebread Professor , Neurological Surgery , Ro Ee Gilron , Hubble Space Telescope , ஒன்றுபட்டது மாநிலங்களில் , பிலிப் நட்சத்திரம் , பார்கின்சன் அடித்தளம் , மெதிடிறோனிக் இன்க் , துறை ஆஃப் நரம்பியல் அறுவை சிகிச்சை , வெயில் நிறுவனம் க்கு நரம்பியல் , இயற்கை உயிரி தொழில்நுட்பவியல் , நரம்பியல் அறுவை சிகிச்சை , ஹப்பிள் இடம் தொலைநோக்கி ,

Pioneering neural recordings lay the groundwork for personalized Parkinson's treatments


Pioneering neural recordings lay the groundwork for personalized Parkinson s treatments
Pioneering neural recordings in patients with Parkinson s disease by UC San Francisco scientists lays the groundwork for personalized brain stimulation to treat Parkinson s and other neurological disorders.
In a study published May 3rd in
Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many months, with and without deep brain stimulation (DBS) therapy. Pairing the brain recordings with wearable monitors of movement, they identified patterns of brain activity corresponding to specific movement abnormalities associated with Parkinson s. Their research provides the first evidence, during normal activities of daily living, for a long-held hypothesis that Parkinson s symptoms are related to erratic brain wave patterns, and demonstrate how DBS restores order to patient brain waves. ....

United States , Roee Gilron , Philip Starr , Emily Henderson , Parkinson Foundation , Department Of Neurological Surgery , Weill Institute For Neurosciences , Nature Biotechnology , Dolores Cakebread Professor , Neurological Surgery , Ro Ee Gilron , Hubble Space Telescope , Brain Stimulation , Deep Brain Stimulation , Arkinson 39s Disease , Al King , ஒன்றுபட்டது மாநிலங்களில் , பிலிப் நட்சத்திரம் , எமிலி ஹென்டர்சன் , பார்கின்சன் அடித்தளம் , துறை ஆஃப் நரம்பியல் அறுவை சிகிச்சை , வெயில் நிறுவனம் க்கு நரம்பியல் , இயற்கை உயிரி தொழில்நுட்பவியல் , நரம்பியல் அறுவை சிகிச்சை , ஹப்பிள் இடம் தொலைநோக்கி , அல் கிங் ,