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Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain


Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain
The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction.
A new preprint on the
bioRxiv server describes the results of a macaque study that showed the development of neurological features of inflammation, following infection by SARS-CoV-2.
Neurological symptoms in SARS-CoV-2 infection
SARS-CoV-2 primarily affects the respiratory organs, but in about a third of hospitalized COVID-19 patients, neurological manifestations are present. These include anosmia or dysgeusia, delirium, impaired consciousness, seizures, or psychosis. Some patients also develop Parkinsonism. ....

Liji Thomas , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Lewy Bodies , Pituitary Gland , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , கொரோனா வைரஸ் , மோசமான உடல்கள் , வளர்சிதை மாற்றம் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Researchers identify a neural pathway critical to correcting behavioral errors


Researchers identify a neural pathway critical to correcting behavioral errors
Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders.
The team s research, published February 19 in
Neuron, also suggests that neurostimulation of this brain pathway could provide an important mechanism for attention adjustments following behavioral errors.
When errors are committed, such as missing a stop sign or running a red light while driving, it s important for our survival to immediately adapt behavior by paying more attention to prevent further errors. This ability to adapt behavior after erroneous actions are one of the key components of human cognitive control. ....

Kevin Norman , Hirofumi Morishita , Emily Henderson , Icahn School Of Medicine At Mount Sinai , Development Institute , Mindich Child Health , Friedman Brain Institute , Associate Professor , Icahn School , Mount Sinai , Study Senior Author , Faculty Member , கெவின் நார்மன் , ஹிரோபூமி மோரிஷிதா , எமிலி ஹென்டர்சன் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , வளர்ச்சி நிறுவனம் , ப்ரைட்மேன் மூளை நிறுவனம் , இணை ப்ரொஃபெஸர் , இக்ஹ்ன் பள்ளி , ஏற்ற சினை , படிப்பு மூத்தவர் நூலாசிரியர் , ஆசிரிய உறுப்பினர் , மன இறுக்கம் , மனநல மருத்துவம் ,

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows


Neurons activated by visual stimulus keep more active during subsequent sleep, study shows
When you slip into sleep, it s easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain.
U-M researchers have been studying how memories associated with a specific sensory event are formed and stored in mice. In a study conducted prior to the coronavirus pandemic and recently published in
Nature Communications, the researchers examined how a fearful memory formed in relation to a specific visual stimulus.
They found that not only did the neurons activated by the visual stimulus keep more active during subsequent sleep, sleep is vital to their ability to connect the fear memory to the sensory event. ....

United States , Brittany Clawson , Sara Aton , Emily Henderson , Um Department Of Molecular , Nature Communications , University Of Michigan , Um Department , Corona Virus , ஒன்றுபட்டது மாநிலங்களில் , பிரிட்டானி கிளாசன் , சாரா ஆதொன் , எமிலி ஹென்டர்சன் , உம் துறை ஆஃப் மூலக்கூறு , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , உம் துறை , கொரோனா வைரஸ் , சர்வதேச பரவல் ,

IAR Systems introduces support for 64-bit Arm cores


IAR Systems introduces support for 64-bit Arm cores
IAR Systems has announced that its C/C++ development toolchain IAR Embedded Workbench for Arm is now able to support 64-bit Arm cores including Arm Cortex-A35, Cortex-A53 and Cortex-A55.
At a time when more applications are being based on 64-bit cores, specifically within low-power applications, deeply embedded and handheld devices, the Embedded Workbench provides customers with diverse microcontroller support as well as adapted licensing options to fit different organisations needs
By supporting leading-edge designs needing the performance from 64-bit Arm cores, IAR Systems can enable its customers to make use of the toolchain’s optimisation technology also for 64-bit devices. In addition, integrated code analysis tools ensure code quality, and for simplified functional safety certification, a pre-certified version of the toolchain is available. ....

Stefan Skarin , Arm Cortex A , Embedded Workbench , Embedded Software , Software Development Tools , ஸ்டீபன் ஸ்காரின் , பதிக்கப்பட்ட வர்க்‌பெஂச் , பதிக்கப்பட்ட மென்பொருள் , மென்பொருள் வளர்ச்சி கருவிகள் ,