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Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells


Key protein helps bacteria that causes Legionnaires disease to set up house in host cells
Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires disease to set up house in the cells of humans and other hosts. The findings, published in
Science, could offer insights into how other bacteria are able to survive inside cells, knowledge that could lead to new treatments for a wide variety of infections.
Many infectious bacteria, from
chlamydia to
salmonella, use systems that allow them to dwell within their host s cells. Better understanding the tools they use to make this happen is teaching us some interesting biochemistry and could eventually lead to new targets for therapy. ....

Vincent Tagliabracci , Emily Henderson , Centers For Disease , Haroldc Simmons Comprehensive Cancer Center , Michaell Rosenberg Scholar In Medical Research , Cancer Prevention Research Institute Of Texas , Comprehensive Cancer , Disease Control , Medical Research , Cancer Prevention , Research Institute , எமிலி ஹென்டர்சன் , மையங்கள் க்கு நோய் , புற்றுநோய் ப்ரெவெந்ஶந் ஆராய்ச்சி நிறுவனம் ஆஃப் டெக்சாஸ் , விரிவான புற்றுநோய் , நோய் கட்டுப்பாடு , மருத்துவ ஆராய்ச்சி , புற்றுநோய் ப்ரெவெந்ஶந் , ஆராய்ச்சி நிறுவனம் ,

How Legionella makes itself at home


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IMAGE: A new study suggests that Legionella (red) oscillates between the endoplasmic reticulum (green), and bubble- or tube-shaped structures (blue) to help create or sustain a structure that houses this bacterium.
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Credit: UT Southwestern Medical Center
DALLAS - May 10, 2021 - Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires disease to set up house in the cells of humans and other hosts. The findings, published in
Science, could offer insights into how other bacteria are able to survive inside cells, knowledge that could lead to new treatments for a wide variety of infections. ....

United States , Adam Osinski , Vincent Tagliabracci , Krzysztof Pawlowski , Victora Lopez , Dianar Tomchick , Centers For Disease , Haroldc Simmons Comprehensive Cancer Center , National Agency For Scientific Exchange , Sowell Family Scholar In Medical Research , Michaell Rosenberg Scholar In Medical Research , Welch Foundation , Cancer Prevention Research Institute Of Texas , Comprehensive Cancer , Disease Control , Medical Research , Cancer Prevention , Research Institute , Ting Sung Hsieh , Jen Liou , Sowell Family Scholar , Polish National Agency , Scientific Exchange , ஒன்றுபட்டது மாநிலங்களில் , மையங்கள் க்கு நோய் , நன்றாக குடும்பம் அறிஞர் இல் மருத்துவ ஆராய்ச்சி ,

Rutgers Cancer Institute of New Jersey Leader Elected as a Member to the National Academy of Sciences


Rutgers Cancer Institute of New Jersey Leader Elected as a Member to the National Academy of Sciences
Eileen White, PhD
Newswise New Brunswick, N.J., April 27, 2021 – Rutgers Cancer Institute of New Jersey Deputy Director, Chief Scientific Officer, and Associate Director for Basic Research Eileen White, PhD, has been elected to the National Academy of Sciences (NAS). She is among 120 members elected this year in recognition of their distinguished and continuing achievements in original research.
The NAS is a private, non-profit society of distinguished scholars charged with providing independent, objective advice to the nation on matters related to science and technology. Members are elected to the NAS by their peers for their outstanding contributions to science. Election to membership in the NAS is considered one of the highest honors that a scientist can receive. ....

United States , Rutgers University , New Jersey , New Brunswick , Stony Brook , Eileen White , Stevenk Libutti , National Cancer Institute , American Society Of Microbiology , Excellence At Rutgers Cancer Institute , Rutgers Cancer Institute Of New Jersey Deputy , National Cancer Comprehensive Center , Rwjbarnabas Health , School Of Arts , Cancer Prevention Research Institute Of Texas , National Academy Of Sciences , American Association For The Advancement Of Science , Rutgers Cancer Institute , National Academy , Rensselaer Polytechnic Institute , Damon Runyon Cancer Research Foundation , American Association For Cancer Research , Bruce Stillman At Cold Spring Harbor Laboratory , Metabolism Center , White Laboratory At Rutgers Cancer Institute , Research Eileen White ,

Aravive Announces First Patient Dosed in Phase 3 Registrational Trial Evaluating AVB-500 in Patients with Platinum Resistant Ovarian Cancer


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U.S. FDA Granted Fast Track Designation in 2018
Trial Expected to Enroll 300-400 Patients at Approximately 165 Sites in the U.S. and Europe in Simplified Adaptive Trial Design
Conference Call and Webcast Today at 8:30 a.m. ET
HOUSTON, April 27, 2021 (GLOBE NEWSWIRE) Aravive Inc. (NASDAQ:ARAV), a clinical-stage oncology company developing innovative therapeutics to treat life-threatening diseases, today announced the Company has dosed the first patient in its Phase 3 trial of AVB-500 in platinum resistant ovarian cancer (PROC). The trial is evaluating the efficacy of AVB-500 in combination with paclitaxel (chemotherapy) and the primary endpoint is progression free survival. ....

United States , Katherine Fuh , Reshma Rangwala , Joseph Schepers , National Cancer Institute , European Network Of Gynaecological Oncological Trial Groups , Reproductive Health Sciences , Cancer Prevention Research Institute Of Texas , Company Annual Report On Form , European Network For Gynaecological Oncological Trial , Product Development Award , Department Of Obstetrics , Drug Administration , Aravive Inc , Washington University School Of Medicine , Division Of Gynecologic Oncology , Foundation Inc , European Society Of Gynaecological Oncology , Addresses High Unmet Medical Need , Advanced Ovarian , Fast Track Designation , Simplified Adaptive Trial , Webcast Today , Associate Professor , Gynecologic Oncology , Washington University School ,