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Study: Why Radiation Therapy Can Lose Potency In Cancer Patients

Radiation therapy is used to treat more than half of all cancer patients, but it's not without its drawbacks. A new study published in the journal Nature Genetics suggests ways to make the treatment more effective.Radiation therapy works by killing tumor cells or damaging their DNA and ability to replicate. But the new study finds cellular repair mechanisms can cause mutations ....

United States , Floris Barthel , Jackson Laboratory For Genomic Medicine In Farmington , Translational Genomics Research Institute , Nature Genetics , Jackson Laboratory , Genomic Medicine , ஒன்றுபட்டது மாநிலங்களில் , புளோரிஸ் பார்தெல் , மொழிபெயர்ப்பு மரபியல் ஆராய்ச்சி நிறுவனம் , இயற்கை ஜெநெடிக்ஸ் , ஜாக்சன் ஆய்வகம் ,

Measuring the effects of radiotherapy on cancer may open up avenues for treatment

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Ionizing radiation is used for treating nearly half of all cancer patients. Radiotherapy works by damaging the DNA of cancer cells, and cells sustaining so much DNA damage that they cannot sufficiently repair it will soon cease to replicate and die. It s an effective strategy overall, and radiotherapy is a common frontline cancer treatment option. Unfortunately, many cancers have subsets of cells that are able to survive initial radiotherapeutic regimens by developing mechanisms that are able to repair the DNA damage. This often results in resistance to further radiation as cancerous growth recurs. But until recently, little was known about exactly what happens in the genomes of cancer cells following radiotherapy. ....

Emre Kocakavuk , Floris Barthel , Roel Verhaak , Jackson Laboratory , University Hospital Essen , Professor Roel Verhaak , Nature Genetics , புளோரிஸ் பார்தெல் , ஜாக்சன் ஆய்வகம் , பல்கலைக்கழகம் மருத்துவமனை எஸெந் , இயற்கை ஜெநெடிக்ஸ் ,