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 E-Mail Ionizing radiation is used for treating nearly half of all cancer patients. Radiotherapy works by damaging the DNA of cancer cells, and cells sustaining so much DNA damage that they cannot sufficiently repair it will soon cease to replicate and die. It s an effective strategy overall, and radiotherapy is a common frontline cancer treatment option. Unfortunately, many cancers have subsets of cells that are able to survive initial radiotherapeutic regimens by developing mechanisms that are able to repair the DNA damage. This often results in resistance to further radiation as cancerous growth recurs. But until recently, little was known about exactly what happens in the genomes of cancer cells following radiotherapy.

Emre kocakavukFloris barthelRoel verhaakJackson laboratoryUniversity hospital essenProfessor roel verhaakNature geneticsபுளோரிஸ் பார்தெல்ஜாக்சன் ஆய்வகம்பல்கலைக்கழகம் மருத்துவமனை எஸெந்இயற்கை ஜெநெடிக்ஸ்