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Abivax reports excellent efficacy and safety of ABX464 in phase 2b clinical trial in ulcerative coli


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24-May-2021
Abivax reports excellent efficacy and safety of ABX464 in phase 2b clinical trial in ulcerative colitis and plans to proceed to phase 3
DGAP-News: ABIVAX
/ Key word(s): Study results
24.05.2021 / 18:30
The issuer is solely responsible for the content of this announcement.
Abivax reports excellent efficacy and safety of ABX464 in phase 2b clinical trial in ulcerative colitis
and plans to proceed to phase 3
Primary endpoint (statistically significant reduction of Modified Mayo Score
[1]) was met with once-daily ABX464 (25mg, 50mg, 100mg) at week 8 in these 254 patients randomized, double-blind and placebo-controlled clinical trial (p ....

New York , United States , France General , United Kingdom , Region Flamande , Pbruce Sands , William Sandborn , Hartmutj Ehrlich , Burrillb Crohn , Philippe Pouletty , Enregistrement Universel , University Hospitals Leuven , Icahn School Of Medicine At Mount Sinai , Distribution Services , Modified Mayo , Tuesday May , Euronext Paris , Icahn School , Mount Sinai , New York City , Mayo Score , Key Secondary Endpoints , Clinical Remission , Clinical Response , Fecal Calprotectin , French Autorit ,

Biostatisticians draft blueprints for COVID-19 vax trials


Biostatisticians draft blueprints for COVID-19 vax trials
Hutch group applies skills honed during decades of HIV prevention trials to bring about safe and effective vaccines for a new pandemic
February 18, 2021

By Sabin Russell
/ Fred Hutch News Service
Dr. Peter Gilbert (left) leads a team of Fred Hutch biostatisticians that pivoted to COVID-19 vaccine trial design. Dr. Holly Janes (right) is a co-principal investigator with Gilbert at the Statistical and Data Management Center for the HIV Vaccine Trials Network.
Dr. Peter Gilbert (top) leads a team of Fred Hutch biostatisticians that pivoted to COVID-19 vaccine trial design. Dr. Holly Janes (below) is a co-principal investigator with Gilbert at the Statistical and Data Management Center for the HIV Vaccine Trials Network. ....

United States , Fred Hutch , Norman Breslow , Francis Collins , Thomas Fleming , Yunda Huang , Ross Prentice , Jim Kublin , Tony Fauci , Holly Janes , Peter Gilbert , Richard Gilbert , Larry Corey , Jessica Andriesen , National Cancer Institute , National Institute Of Allergy , Pacific Northwest National Laboratory , Data Management Center , University Of Washington , Prevention Network , Vaccine Trials Network , Fred Hutchinson Cancer Research Center , National Institutes Of Health , Drug Administration , Hutch Public Health Sciences Division , Uw Department Of Biostatistics ,