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Cancer News from AACR's 2021 Meeting: Targeted Therapy and Immunotherapy

Canva; Everyday Health
The annual meeting of the American Association for Cancer Research (AACR) is one of the largest cancer research meetings of its kind, bringing together a range of researchers, from those who spend their time in the lab to those who focus on patients in the clinic. The meeting atmosphere is electric even when it’s virtual. Here are five key studies that stood out during the first week of the virtual AACR meeting, held April 10–15, 2021.
Lymphoma Progression Cut in Half When Rituxan Is Paired With Aliqopa
What’s new Patients with relapsed indolent non-Hodgkin lymphoma saw a 48 percent reduced risk of progression (time without the disease advancing or death) when the targeted therapy Aliqopa (copanlisib) was used in combination with Rituxan (rituximab) versus Rituxan alone. Rituxan alone is the current standard therapy for relapses. The results, which come from a phase 3 trial known as CHRONOS-3, were announced at the AACR meeting and simu ....

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Immune-boosting drug may help before lung cancer surgery | iNFOnews | Thompson-Okanagan's News Source

Immune-boosting drug may help before lung cancer surgery | iNFOnews | Thompson-Okanagan's News Source
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Opdivo plus chemotherapy increases response in pre-surgery NSCLC patients

Opdivo plus chemotherapy increases response in pre-surgery NSCLC patients
Combination increases complete response rate to 24% compared to chemotherapy alone
Bristol Myers Squibb’s PD-1 inhibitor Opdivo has scored a new win in the pre-surgery, non-small cell lung cancer (NSCLC) setting.
Data presented at the virtual American Association for Cancer Research (AACR) annual meeting showcased results from the CheckMate-816 study, which evaluated Opdivo (nivolumab) plus chemotherapy in patients with early-stage NSCLC before surgery.
The primary endpoints of the study were pathological complete response (pCR), defined as no residual viable tumour in the resected lung specimen and the sampled lymph node after surgery and event-free survival (EFS). ....

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Immune-boosting drug may help before lung cancer surgery

Immune-boosting drug may help before lung cancer surgery
MARILYNN MARCHIONE, AP Chief Medical Writer
April 12, 2021
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FILE - This product image provided by Bristol-Myers Squibb shows their drug Opdivo. On Saturday, April 10, 2021, doctors say that the drug, which helps the immune system fight cancer, gave dramatic results when used with chemotherapy before surgery in patients with operable lung tumors. (Bristol-Myers Squibb via AP)AP
A drug that helps the immune system fight cancer gave dramatic results when used with chemotherapy before surgery in patients with operable lung tumors, doctors report.
One out of 4 patients given chemo and the Bristol Myers Squibb drug Opdivo had no signs of cancer remaining once they ultimately had surgery, a study of about 350 such people found. ....

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Immune-boosting drug may help before lung cancer surgery | iNFOnews | Thompson-Okanagan's News Source

Marilynn Marchione
FILE - This product image provided by Bristol-Myers Squibb shows their drug Opdivo. On Saturday, April 10, 2021, doctors say that the drug, which helps the immune system fight cancer, gave dramatic results when used with chemotherapy before surgery in patients with operable lung tumors. (Bristol-Myers Squibb via AP)
April 12, 2021 - 9:55 AM
A drug that helps the immune system fight cancer gave dramatic results when used with chemotherapy before surgery in patients with operable lung tumors, doctors report.
One out of 4 patients given chemo and the Bristol Myers Squibb drug Opdivo had no signs of cancer remaining once they ultimately had surgery, a study of about 350 such people found. ....

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