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F. Hoffmann-La Roche Ltd: Roche's faricimab meets primary endpoint in two global phase III studies and shows potential to extend time between treatments up to 16 weeks for people with neovascular age-related macular degeneration

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Faricimab given at intervals of up to every 16 weeks demonstrated non-inferior visual acuity gains compared to aflibercept given every eight weeks, potentially reducing the frequency of injections and overall burden of treatment
Nearly half of people were treated with faricimab every 16 weeks during the first year - the first time this level of durability has been achieved in a phase III study of an injectable eye medicine for neovascular age-related macular degeneration
Faricimab is the first investigational bispecific antibody designed for the eye and targets two distinct pathways - via angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A) - that drive a number of retinal conditions ....

United States , Nathalie Meetz , Levi Garraway , Daniel Grotzky , Jon Kaspar Bayard , Karl Mahler , Sabine Borngr , Gerard Tobin , Bruno Eschli , Birgit Masjost , Lisa Tuomi , Loren Kalm , Patrick Barth , Karsten Kleine , Lancet Global Health , Drug Administration , Head Of Global Product Development , American Society Of Retina Specialists Annual Meeting , Brightfocus Foundation , Roche Group , European Medicines Agency , Pharmaceuticals Industry , Roche Group Media Relations , Chief Medical Officer , Global Product , Bascom Palmer Eye Institute ,

Roche's faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness – IT Business Net

Roche's faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness – IT Business Net
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Investegate |F. Hoffmann-La Roche Ltd Announcements | F. Hoffmann-La Roche Ltd: Roche's faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness

F. Hoffmann-La Roche Ltd
Roche’s faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness
Roche’s faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness
Faricimab given every eight weeks and at personalised dosing intervals of up to 16 weeks demonstrated non-inferior visual acuity gains compared to aflibercept given every eight weeks in both studies
More than half of participants in the faricimab personalised dosing arms had extended time between treatments to 16 weeks at year one – the first time this level of durability has been achieved in a phase III diabetic macular edema study ....

United States , United Kingdom , Nathalie Meetz , Levi Garraway , Daniel Grotzky , Patrick Barth , Karsten Kleine , Head Of Global Product Development , American Academy Of Ophthalmology , American Optometric Association , American Society Of Retina Specialists Annual Meeting , National Eye Institute , Roche Group , Pharmaceuticals Industry , Roche Group Media Relations , Chief Medical Officer , Global Product , Bascom Palmer Eye Institute , Miami Miller School , Port Delivery System , World Health Organization Model Lists , Essential Medicines , Dow Jones Sustainability Indices , Chugai Pharmaceutical , Macula Lutea , British Journal ,