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Student project on understanding emerging diseases via internet searches


You’re not feeling well so you open a search engine and type: fever, dry cough, hoping to find hints of what you may have. A handful of days later, you’re feeling worse, and you type in: trouble breathing. It turns out you’re not the only one who’s doing this, and a Harvard senior’s research project suggests that tracking the results of all those searches can tell us something about the progression of a new disease in individuals and through a population.
Tina Lu, a Leverett House computer science concentrator, analyzed search engine data from Google Trends going back to the beginning of the coronavirus pandemic to see how well symptom searches in 32 countries on six continents matched the clinical symptoms of COVID-19 and whether the number of searches served as a harbinger of rising incidence of cases. ....

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Researchers examine effectiveness of Pfizer vaccine against COVID-19


Researchers examine effectiveness of Pfizer vaccine against COVID-19
A major study, conducted in collaboration with researchers from Harvard University, examined data on 600,000 vaccinated individuals in Israel, along with 600,000 matched unvaccinated controls.
Two doses of Pfizer/BioNTech vaccine reduced symptomatic COVID-19 by 94% and severe disease by 92%; Single-dose reduced symptomatic COVID-19 by 57% and severe disease by 62%; Vaccine effectiveness was found to be similar across age groups; B.1.1.7 variant became dominant in Israel during the study period.
The Clalit Research Institute, in collaboration with researchers from Harvard University, analyzed one of the world s largest integrated health record databases to examine the effectiveness of the Pfizer vaccine against COVID-19. ....

United States , Harvard University , Mark Katz , Miguel Hern , Marc Lipsitch , Eldad Kepten , Shai Perchik , Noam Barda , Emily Henderson , Oren Miron , Ben Reis , Noa Dagan , Predictive Medicine Group At Boston Children Hospital , Israel National Expert Advisory Team , Clalit Research Institute , Harvard Medical School , Ran Balicer , Public Health , Boston Children , Harvard Medical , Chief Innovation Officer , National Expert Advisory Team , Communicable Disease Dynamics , Predictive Medicine Group , Clinical Trial , Corona Virus ,

Real-world effectiveness of COVID-19 vaccine - research by Clalit Research Institute


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The Clalit Research Institute, in collaboration with researchers from Harvard University, analyzed one of the world s largest integrated health record databases to examine the effectiveness of the Pfizer vaccine against COVID-19. The study provides the first large-scale peer-reviewed evaluation of the effectiveness of a COVID-19 vaccine in a nationwide mass-vaccination setting. The study was conducted in Israel, which currently leads the world in COVID-19 vaccination rates.
The results of this study validate and complement the previously reported findings of the Pfizer/BioNTech Phase-III randomized clinical trial, which focused on symptomatic infections, and which, with 21,720 vaccinated individuals, could not precisely assess vaccine effectiveness against severe disease in the fully vaccinated. The present study s large size allows a more detailed assessment of the vaccine s effectiveness in preventing a wider range of outcomes, across different time periods and ....

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