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New drug molecules could prevent skin ageing caused by sun exposure


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Two new molecules that generate minute amounts of the gas hydrogen sulfide have been found to prevent skin from ageing after being exposed to ultraviolet light found in sunlight.
Sunburn is a major cause of premature ageing in skin, and a primary risk factor for skin cancer, and other skin problems associated with ageing. Now, an international research team has made inroads towards being able to reverse or delay this damage for the first time.
The research was led by Professor Matt Whiteman at the University of Exeter Medical School, and Professor Uraiwan Panich at the Faculty of Medicine Siriraj Hospital, Mahidol University, in Thailand. In the study published in Antioxidant and Redox Signaling, the team exposed adult human skin cells and the skin of mice to ultraviolet radiation (UVA). UVA is the part of natural sunlight which damages unprotected skin and can penetrate through windows, and even through some clothes. It causes skin to a ....

Krung Thep Mahanakhon , Uraiwan Panich , Matt Whiteman , University Of Exeter Medical School , Mahidol University , University Of Exeter , Professor Matt Whiteman , Exeter Medical School , Professor Uraiwan Panich , Medicine Siriraj Hospital , Redox Signaling , Mitorx Therapeutics , மேட் வைட்மேன் , பல்கலைக்கழகம் ஆஃப் எக்ஸெடர் மருத்துவ பள்ளி , பல்கலைக்கழகம் ஆஃப் எக்ஸெடர் , ப்ரொஃபெஸர் மேட் வைட்மேன் , எக்ஸெடர் மருத்துவ பள்ளி , ரெடாக்ஸ் சமிக்ஞை ,

Study paves the way to a potential new treatment for rare terminal childhood illness


Study paves the way to a potential new treatment for rare terminal childhood illness
Scientists at the University of Exeter have identified a way to rescue cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease.
The research, funded by the United Mitochondrial Disease Foundation in the USA, was led by Professors Matt Whiteman and Tim Etheridge. In the study, published in the
Journal of Inherited Metabolic Disease, the team used novel drugs being developed at the University of Exeter, which metabolically reprogramme mitochondria - the cellular energy production centres in cells, by providing them with an alternative fuel source to generate metabolic energy in the form of minute quantities of hydrogen sulfide. ....

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New drug molecules hold promise for treating rare inherited terminal childhood disease


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Scientists at the University of Exeter have identified a way to rescue cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease.
The research, funded by the United Mitochondrial Disease Foundation in the USA, was led by Professors Matt Whiteman and Tim Etheridge. In the study, published in the
Journal of Inherited Metabolic Disease, the team used novel drugs being developed at the University of Exeter, which metabolically reprogramme mitochondria - the cellular energy production centres in cells, by providing them with an alternative fuel source to generate metabolic energy in the form of minute quantities of hydrogen sulfide. ....

United States , Tim Etheridge , Matt Whiteman , United Mitochondrial Disease Foundation , University Of Exeter , Professors Matt Whiteman , Inherited Metabolic Disease , Professor Matt Whiteman , ஒன்றுபட்டது மாநிலங்களில் , நேரம் ஈதர்ஜ் , மேட் வைட்மேன் , ஒன்றுபட்டது மைட்டோகாண்ட்ரியல் நோய் அடித்தளம் , பல்கலைக்கழகம் ஆஃப் எக்ஸெடர் , ப்ரொஃபெஸ்ஸர்ஸ் மேட் வைட்மேன் , பரம்பரை வளர்சிதை மாற்ற நோய் , ப்ரொஃபெஸர் மேட் வைட்மேன் ,