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Top News In மரபணு அட்லஸ் ஆராய்ச்சி வலைப்பின்னல் Today - Breaking & Trending Today

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients


New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients
A new test that measures the quantity and quality of inactive HIV viruses in the genes of people living with HIV may eventually give researchers a better idea of what drugs work best at curing the disease.
Currently no cure exists for HIV and AIDS, but antiretroviral therapy drugs, or ARTs, effectively suppress the virus to undetectable levels.
Published today in
Cell Reports Medicine, the study discusses how a new test, developed jointly by scientists at the University of Washington School of Medicine and Fred Hutchinson Cancer Research Center, will give researchers, and eventually doctors, an easier way to gauge how much HIV virus might reside in a patient s genome. ....

Claire Levy , Florian Hladik , Emily Henderson , University Of Washington School Medicine , Fred Hutchinson Cancer Research Center , Cell Reports Medicine , Washington School , கிளாரி வசூல் செய்தல் , புளோரியன் லதிக் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் பள்ளி மருந்து , ஃப்ரெட் ஹட்சின்சன் புற்றுநோய் ஆராய்ச்சி மையம் , செல் அறிக்கைகள் மருந்து , வாஷிங்டன் பள்ளி ,

South Africa SARS-CoV-2 variant B.1.351 easily escapes Sputnik vaccine


South Africa SARS-CoV-2 variant B.1.351 easily escapes Sputnik vaccine
The current pandemic of novel coronavirus disease 2019 (COVID-19) was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has undergone numerous mutations in its genome to emerge as different variants. As of now, a dozen vaccines have received emergency use authorization, and many countries around the world have initiated mass vaccination campaigns.
A new preprint research paper posted to the
medRxiv server reports on vaccine resistance data that pushes the end of the pandemic further away.
Variants of concern and spike mutations
Most vaccines now in use or being developed focus on generating antibodies to the viral spike protein, which mediates host cell entry and infection. This is based on the strong correlation between neutralizing antibodies to the spike and protective immunity. ....

South Africa , United States , United Kingdom , South African , Liji Thomas , Astrazeneca Chadox , Bright Panel , South American , South America , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , சரி குழு , தெற்கு அமெரிக்கன் , தெற்கு அமெரிக்கா , கொரோனா வைரஸ் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

CAL20.C SARS-CoV-2 variant skyrocketing in California evades host immune response


CAL20.C SARS-CoV-2 variant skyrocketing in California evades host immune response
The effect of different neutralizing antibodies, both vaccine-elicited and from convalescent sera, suggests new variants are emerging that can evade the human immune response.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to host cells via its spike protein, which has two parts, the S1 and S2 subunits. The S1 subunit has the receptor-binding domain (RBD) and the N-terminal domain (NTD). The RBD binds to the host angiotensin-converting enzyme 2 (ACE2) to infect host cells.
Neutralizing antibodies are produced against both the RBD and NTD by infected and vaccinated individuals. Some RBD-specific monoclonal antibodies are currently under clinical trials or approved for use to treat COVID-19 patients. ....

United States , Lakshmi Supriya , United States Centers For Disease Control , Phd Apr , United States Centers , Disease Control , Immune Response , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , ஒன்றுபட்டது மாநிலங்களில் , லட்சுமி சுப்ரியா , ஒன்றுபட்டது மாநிலங்களில் மையங்கள் க்கு நோய் கட்டுப்பாடு , ஃப்ட் ஏப்ரல் , ஒன்றுபட்டது மாநிலங்களில் மையங்கள் , நோய் கட்டுப்பாடு , நோய் எதிர்ப்பு சக்தி பதில் , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

High expression of cell death genes may increase risk of early death from lung cancer


High expression of cell death genes may increase risk of early death from lung cancer
Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.
Also seemingly paradoxically, patients with high expression of this 21-gene cell death signature the researchers have identified, have indicators that their immune system is attacking the cancer, like higher levels of cytotoxic T cells, which typically kill cancer.
But they also have high levels of molecules that can suppress those T cells, helping transform them into dysfunctional, exhausted T cells, they report in the journal ....

United States , Ravindra Kolhe , Emily Henderson , Centers For Disease , National Cancer Institute , National Human Genome Research Institute , Drug Administration , Cancer Research Institute , College Of Georgia Department Pathology , Georgia Esoteric , Medical College , Georgia Department , Cancer Genome Atlas , National Human Genome Research , Disease Control , Cancer Research , Cell Death , Lung Cancer , Immune System , Pd L1 , ஒன்றுபட்டது மாநிலங்களில் , ரவின்ற கொள்ே , எமிலி ஹென்டர்சன் , மையங்கள் க்கு நோய் , தேசிய புற்றுநோய் நிறுவனம் , தேசிய மனிதன் மரபணு ஆராய்ச்சி நிறுவனம் ,