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Optical genome mapping could change the existing workflow within cytogenetic laboratories


Optical genome mapping could change the existing workflow within cytogenetic laboratories
Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately. Sometimes even better than all existing techniques together, as they describe in two proof-of-concept studies published in the
American Journal of Human Genetics.
This new technique could radically change the existing workflow within cytogenetic laboratories.
Human hereditary material is stored in 46 chromosomes (23 pairs). Although those chromosomes are quite stable, changes in number or structure can still occur. A well-known example is Down syndrome, which is caused by an extra chromosome 21 (trisomy 21). An extra chromosome makes a big difference and is quite easy to visualize. But all kinds of other, smaller changes can occur as well in chromosomes. ....

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Nucleome Therapeutics announces publication of a novel method enabling 3D genome mapping at single base pair resolution in the journal Nature

Nucleome Therapeutics announces publication of a novel method enabling 3D genome mapping at single base pair resolution in the journal Nature New method is being used by Nucleome to unlock the dark matter of the human genome for drug target discovery with exceptional precision Oxford, UK, 10 June 2021 – Nucleome Therapeutics (“Nucleome”), a biotechnology company decoding the dark matter of the human genome to uncover novel ways to treat disease, today announces the publication of a novel 3D geno ....

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