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Antibiotic may improve outcomes for depression in people with low level inflammation

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King s College London researchers have found evidence that minocycline, a widely used antibiotic with anti-inflammatory properties, gave greater improvement in depressive symptoms in patients with treatment resistant depression with low-grade peripheral inflammation.
Improvement in depressive symptoms
In a four-week randomised clinical MINDEP (MINocycline in DEPression) trial, 39 patients with major depressive disorder were recruited from services linked to South London and Maudsley NHS Foundation Trust (SLaM) and via public advertisement.
The trial took place at the NIHR / Wellcome Trust King s Clinical Research Facility at King s College Hospital. The patients, who were taking their routine antidepressant treatment, were split into two groups, one group took daily a placebo (sugar pill) tablet while the other group took daily minocycline alongside their routine treatment for 4 weeks. ....

United Kingdom , City Of , Maria Antonietta Nettis , Serena Rianjongdee , Valeria Mondelli , King College London , National Institute For Health Research , Clinical Research Associate At Institute Of Psychiatry , Department Of Health , Institute Of Psychiatry , Maudsley Biomedical Research Centre , Foundation Trust Sla , Qs World University Rankings , College London , South London , Wellcome Trust King , Clinical Research Facility , Hamilton Depression , Clinical Reader , Principal Investigator , Clinical Research Associate , National Institute , Health Research , Engagement Manager , Biomedical Research Centre , Engagement Officer ,

Antibiotic may improve depressive symptoms in people with low-level inflammation: Study

Antibiotic may improve depressive symptoms in people with low-level inflammation: Study
ANI |
Updated: Jan 28, 2021 11:29 IST
Washington [US], January 28 (ANI): While antibiotics are widely used to treat bacterial infections and other illnesses, a new research suggested that minocycline, an antibiotic with anti-inflammatory properties, improved depressive symptoms in patients with low-grade peripheral inflammation.
The findings of the study were published in the journal Neuropsychopharmacology . According to the study led by King s College London researchers minocycline helped in improving depressive symptoms in patients with treatment-resistant depression with low-grade peripheral inflammation.
In a four-week randomised clinical MINDEP (MINocycline in DEPression) trial, 39 patients with major depressive disorder were recruited from services linked to South London and Maudsley NHS Foundation Trust (SLaM) and via public adv ....

United States , City Of , United Kingdom , Maria Antonietta Nettis , Valeria Mondelli , King College London , Clinical Research Associate At Institute Of Psychiatry , Foundation Trust Sla , College London , South London , Wellcome Trust King , Clinical Research Facility , Hamilton Depression , Clinical Reader , Principal Investigator , Clinical Research Associate , Depressive Symptoms , Low Level Inflammation , ஒன்றுபட்டது மாநிலங்களில் , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , வலேரியா மோந்தேள்ளி , கிங் கல்லூரி லண்டன் , மருத்துவ ஆராய்ச்சி இணை இல் நிறுவனம் ஆஃப் மனநல மருத்துவம் , அடித்தளம் நம்பிக்கை சில , கல்லூரி லண்டன் ,