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Drug to Treat Low Sexual Desire in Women Has Mild Effect


Drug to Treat Low Sexual Desire in Women Has Mild Effect
by Angela Mohan on 
March 8, 2021 at 6:11 PM
The analysis, published in the peer-reviewed
Journal of Sex Research, also highlights issues with the validity of HSDD as a diagnosis. The condition was removed from the American Diagnostic and Statistical Manual of Mental Disorders (DSM-5) in 2013.
Professor Glen Spielmans, of Metropolitan State University, USA, examined data from bremelanotide s FDA New Drug Application, the clinicaltrials.gov protocol entries for the two 24-week Phase III trials, and the journal article (Kingsberg et al., published in
Obstetrics and Gynecology) that reported both trials.
He also conducted a meta-analysis of efficacy and dropout data appearing in the FDA application and compared these outcomes to those reported in the journal paper. ....

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Genetic variation associated with COVID-19 outcome


Genetic variation associated with COVID-19 outcome
The severity of outcome from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is widely varied, with most individuals remaining asymptomatic while others experience severe life-threatening pneumonia and multi-organ failure. Host genetics play a role in disease progression and prognosis. A paper recently uploaded to the preprint server
et al. (1
st March 2021) identifies several alleles associated with the gene natriuretic peptide receptor C (NPR3) that may impact disease severity.
How was the study performed?
The group worked with 4,488 high-risk COVID-19 outpatients being over 40 years of age and having at least one other comorbidity such as diabetes or obesity. The group was split into two equal sizes, one of which received a placebo, while the other received 0.5 mg colchicine, an anti-inflammatory, daily for a month. The patients were evaluated for disease symptoms 15 and 30 days into ....

Michael Greenwood , Image Credit , Chromosome 9 , Corona Virus , Coronavirus Disease Covid 19 , Sars Cov 2 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , மைக்கேல் கிரீன்வுட் , படம் கடன் , கொரோனா வைரஸ் , நீரிழிவு நோய் , உடல் பருமன் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Microdosing Benefits Might Be Largely Placebo, Experimental Study Suggests


Microdosing Benefits Might Be Largely Placebo, Experimental Study Suggests
Photo: Peter Dejong (AP)
The sometimes hyped benefits of microdosing regularly using small amounts of psychedelic drugs like lysergic acid diethylamide (LSD) might be overstated, new research this week suggests. The study found that people who microdosed did experience psychological benefits, including greater sense of well-being, but that these benefits weren’t substantially different from how others felt when they took a placebo instead. The experimental study’s findings indicate that at least some of the positives of microdosing can be attributed to the placebo effect, but the study does have its own caveats. ....

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