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Not long ago, Moderna had plenty of doubters


‘When the spotlight found Moderna, they were ready’: How the Cambridge biotech company became a world renowned success story
Scott Kirsner
A year ago, Moderna was not on anyone’s “Most Likely to Succeed” list.
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As the Cambridge biotech approached its 10th year, the company had yet to get a single product approved for sale by government regulators. Investors weren’t particularly hot on its potential, either ― after going public in December 2018, Moderna’s stock price hadn’t done much over the ensuing 12 months.
There was skepticism about the company’s approach using custom-crafted RNA to instruct the body’s cells to battle a disease or virus ― partly because Moderna hadn’t disclosed much data about it. And there were questions about its focus on a dim corner of the biotechology industry that, in the words of biotech entrepreneur and former Biogen research executive Michael Gilman, was “neither sexy n ....

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Tracker: The latest on COVID-19 vaccine front-runners


Tracker: The latest on COVID-19 vaccine front-runners
Felice J. Freyer
© Ryan Huddle Globe staff / Adobe stock
While the timing of a vaccine becoming available remains uncertain, there’s no shortage of drug companies and laboratories trying to get one approved.
Each prospective vaccine goes through three phases of study in humans. To speed the process, some vaccine developers are conducting two of the phases simultaneously.
Phase 1: Trials involve small numbers of people, testing whether the vaccine is safe and provokes an immune response.
Phase 2: Trials expand to hundreds of people, comparing the vaccine’s effects in different groups and further testing its safety. ....

New Brunswick , South Africa , France General , United Kingdom , United States , City Of , Curevac Tubingen , Wyc Grousbeck , Novavax Gaithersburg , Stephane Bancel , Moderna Cambridge , Astrazeneca Cambridge , Novartis Basel , Merck Kenilworth , Sinovac Biotech , University Of Oxford , Biomedical Advanced Research , Boston Celtics , Development Authority , Coalition For Epidemic Preparedness Innovations , European Union , European Investment Bank , Ryan Huddle Globe , New England , New York City , European Investment ,

Tracker: The latest on COVID-19 vaccine frontrunners


Tracker: The latest on COVID-19 vaccine front-runners
Felice J. Freyer
© Ryan Huddle Globe staff / Adobe stock
While the timing of a vaccine becoming available remains uncertain, there’s no shortage of drug companies and laboratories trying to get one approved.
Each prospective vaccine goes through three phases of study in humans. To speed the process, some vaccine developers are conducting two of the phases simultaneously.
Phase 1: Trials involve small numbers of people, testing whether the vaccine is safe and provokes an immune response.
Phase 2: Trials expand to hundreds of people, comparing the vaccine’s effects in different groups and further testing its safety. ....

New York , United States , New Brunswick , South Africa , France General , United Kingdom , City Of , Curevac Tubingen , Wyc Grousbeck , Novavax Gaithersburg , Stephane Bancel , Moderna Cambridge , Astrazeneca Cambridge , Novartis Basel , Merck Kenilworth , Sinovac Biotech , University Of Oxford , Biomedical Advanced Research , Boston Celtics , Development Authority , Coalition For Epidemic Preparedness Innovations , European Union , European Investment Bank , Ryan Huddle Globe , New England , New York City ,