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Science s COVID-19 reporting is supported by the Pulitzer Center and the Heising-Simons Foundation
Last-minute vaccine dosing changes that could gamble away proven COVID-19 protection and undermine public trust. Controversial approvals without any efficacy data. Vaccinemakers at odds with countries hosting their clinical trials. The COVID-19 vaccine landscape keeps changing almost daily, simultaneously raising hopes and triggering confusion and scientific debates. “It s crazy,” says vaccine researcher John Moore of Weill Cornell Medicine. “Every morning, it s just, ‘What s going on?’”
Over the past few weeks, COVID-19 vaccines developed in the United Kingdom, China, and India moved toward widespread rollout, offering new weapons in the face of fast-spreading viral variants that threaten to deepen the crisis (see p. 108). But many came with controversies, and U.K. regulators sparked a debate when they endorsed a sharp departure from the expected dosing schedule ....

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