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OncoHost Wins Frost & Sullivan 2021 Technology Innovation Leadership Award for Excellence in Best Practices

OncoHost Wins Frost & Sullivan 2021 Technology Innovation Leadership Award for Excellence in Best Practices Leading Award Recognizes OncoHost’s Commitment to Innovation and Significant Accomplishments in Advancing Predictive Analytics to Improve Cancer Care BINYAMINA, Israel – August 18, 20. ....

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Frontiers | Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model

1
1Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, United States
2Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, United States
3Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, United States
4Department of Pathology, Division of Molecular and Cellular Pathology, University of Alabama at Birmingham, Birmingham, AL, United States
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional
in vitro studies fail to replicate the complexity of these interactions. Herein, we developed three-dimensional (3D) lung tumor models that mimic the human TME and demonstrate tumor-stromal crosstalk mediated by extracellular vesicles (EVs). EVs released by tumor cells, independent of p53 status, and fibroblasts w ....

New York , United States , Franklin Lakes , Fort Collins , San Diego , South Korea , La Jolla , Malvern Panalytical , Olaf Kutsch , Georgem Jr , Victor Thannickal , Ebrahimi Warkianim Upregulation , Biochim Biophys Acta , Santa Clara , Razavi Bazaz , Agilent Technologies , Pathology Core Research Lab , Living Image Software Perkin Elmer , A Powerful Tool In Tumor Research , National Cancer Institute Center Support Grant , Imaging Software , Modified Eagle , Atlas Biologicals , American Type Culture Collection , Supplemental Figure , Detection Kit ,