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Linked Clusters of SARS-CoV-2 Variant B.1.351 — Maryland, January–February 2021


What is already known about this topic?
In January 2021, a SARS-CoV-2 specimen from a Maryland resident was determined to be the B.1.351 variant, first identified in South Africa. The SARS-CoV-2 B.1.351 variant might elicit a reduced neutralizing antibody response.
What is added by this report?
Investigation identified two linked clusters of SARS-CoV-2 infection, comprising 17 total patients (two were hospitalized and one died) who did not report recent travel. Four patients’ specimens were sequenced; all were the B.1.351 variant.
What are the implications for public health practice?
These were the first identified clusters of B.1.351 in the United States with no link to travel. Completed contact investigations, expanded genetic sequencing, and universal prevention strategies, including vaccination, masking, and distance, might prevent the spread of SARS-CoV-2 variants of concern, including B.1.351. ....

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COVID-19 strain of UK variant confirmed in Maryland, Hogan says


The Maryland state public health lab confirmed the first two cases of the U.K. variant of COVID-19 in the state, Gov. Larry Hogan announced Tuesday.|| Coronavirus updates | Maryland s latest numbers | Where to get tested ||The governor said the case involves an Anne Arundel County couple younger than 65. One of the individuals traveled abroad to multiple countries and multiple continents and is thought to have infected their spouse. Both are in isolation, and the state is conducting contact tracing. Neither patient has required hospitalization.Many unknown questions remain unanswered about this case, including when the travel took place and when the couple became sick.The governor said a private lab initially handled the test and found some strange sequences they didn t understand. They sent it to the Maryland state public health lab, which confirmed the U.K. strain. The state lab also sent the test to the Centers for Disease Control and Prevention, which also confirmed the U ....

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