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FDA approves Oncopeptides' PEPAXTO ( melphalan flufenamide) for patients with relapsed or refractory multiple myeloma


FDA approves Oncopeptides PEPAXTO ( melphalan flufenamide) for patients with relapsed or refractory multiple myeloma
STOCKHOLM, Feb. 26, 2021 /PRNewswire/ Oncopeptides AB (publ) (Nasdaq Stockholm: ONCO
), a global biotech company focused on the development of therapies for difficult-to-treat hematological diseases, today announced that the U.S. Food and Drug Administration, FDA, has approved PEPAXTO
(melphalan flufenamide, also known as melflufen), in combination with dexamethasone, for the treatment of adult patients with relapsed or refractory multiple myeloma, who have received at least four prior lines of therapy and whose disease is refractory to at least one proteasome inhibitor, one immunomodulatory agent, and one CD38-directed monoclonal antibody. ....

United States , United Kingdom , Martyj Duvall , Anders Martin , Ola Landgren , Rolf Gulliksen , Klaas Bakker , Linda Holmstr , Jakob Lindberg , Leader Of Experimental Therapeutics Program , Myeloma Program , Sylvester Comprehensive Cancer Center , Drug Administration , Global Head Of Corporate Communications , University Of Miami Health System In , Division Of Hematology , Nasdaq Stockholm , Chief Executive Officer , New Drug Application , Chief Scientific Officer , Professor Ola Landgren , Experimental Therapeutics Program , Miami Health System , Overall Response Rate , Median Duration , Extra Medullary Disease ,

NKTR Teams Up With MRK, Pfizer Initiates Multiple Myeloma Trial, PCSA On Watch


NKTR Teams Up With MRK, Pfizer Initiates Multiple Myeloma Trial, PCSA On Watch
KENILWORTH (NJ) (dpa-AFX) - Today s Daily Dose brings you news about Nektar s collaboration with Merck; Pfizer initiating a refractory multiple myeloma study; Processa Pharma s strategic financing; and vTv Therapeutics initiation of a phase 1 multiple ascending dose study of HPP737.
Read on.
1. Nektar Teams Up With Merck
Nektar Therapeutics (NKTR) has entered into a clinical trial collaboration and supply agreement with Merck (MRK) for a Phase 2/3 study of Bempegaldesleukin in combination with KEYTRUDA for first-line treatment of patients with metastatic or unresectable recurrent squamous cell carcinoma of the head and neck. ....

Newsoara Biopharma , Albert Bourla , Processa Pharma , Predictive Oncology Inc , Shineco Inc , European Commission , Aikido Pharma Inc , Tv Therapeutics Inc , Processa Pharmaceuticals Inc , Interpace Biosciences Inc , Pfizer Inc , Cap Ltd , Daily Dose , Teams Up With , Initiates Multiple Myeloma , Chief Executive Officer , Strengthens Balance , Processa Pharmaceuticals , Necrobiosis Lipoidica , ப்ரிடிக்டிவ் புற்றுநோயியல் இன்க் , ஐரோப்பிய தரகு , அகிடொ பார்மா இன்க் , தொலைக்காட்சி சிகிச்சை இன்க் , ஃபைசர் இன்க் , தொப்பி லிமிடெட் , தினசரி டோஸ் ,

New Recommendations to Eliminate Racial Bias in Blood Cancer Trials


New Recommendations to Eliminate Racial Bias in Blood Cancer Trials
by Colleen Fleiss on 
February 18, 2021 at 11:12 PM
New recommendations are being designed to address the under-representation of African Americans in clinical trials for multiple myeloma (MM), a blood cancer that is twice as deadly in this demographic as in whites, said researchers from Dana-Farber Cancer Institute, the U.S. Food and Drug Administration (FDA) and the American Association for Cancer Research (AACR).
Researchers from Dana-Farber Cancer Institute, the U.S. Food and Drug Administration (FDA) and the American Association for Cancer Research (AACR) are releasing recommendations designed to address the under-representation of African Americans in clinical trials for multiple myeloma (MM), a blood cancer that is twice as deadly in this demographic as in whites. ....

United States , Homeopathycancer Factscancertattoos , Nicole Gormley , Lola Fashoyin , Lisa Ray , Dana Farber Cancer Institute Kennethc Anderson , Jerome Lipper Multiple Myeloma Center , Drug Administration , Bombay Blood Group , American Association For Cancer Research , Lebow Institute For Myeloma Therapeutics , Dana Farber Cancer Institute , Health Benefits Of Dandelion Plant , African American , American Association , Cancer Research , Blood Cancer Discovery , Lebow Institute , Myeloma Therapeutics , Jerome Lipper Multiple Myeloma , Lola Fashoyin Aje , Regulatory Science , Policy Subcommittee , Deepa Mehta , New Treatment Option , Reverse Treatment Resistance ,

Immunomodulatory drugs improve the success rate of cancer therapies


Immunomodulatory drugs improve the success rate of cancer therapies
Immunomodulatory drugs, including the Contergan derivatives lenalidomide and pomalidomide, have significantly improved the therapy of hematologic malignancies such as multiple myeloma.
Researchers at the Technical University of Munich (TUM) have now further decoded the mode of action in this class of medications. At the same time, they identified new innovative targeted cancer therapies.
The drug thalidomide was sold as a sedative under the trade name Contergan in the 1950s and 1960s. At the time, its side-effects triggered one of the largest pharmaceutical scandals in history: The medication was taken from the market after it became known that the use of Contergan during pregnancy had resulted in over 10,000 cases of severe birth defects. ....

Arne Skerra , Vanesa Fern , Florian Bassermann , Michael Heider , Wolfgang Weber , Emily Henderson , Technical University Of Munich , Professor For Nuclear Medicine , Technical University , Nuclear Medicine , Biological Chemistry , Birth Defects , Multiple Myeloma , வனேசா ஃபெர்ன் , மைக்கேல் ஹைடர் , ஓநாய் வெபர் , எமிலி ஹென்டர்சன் , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் முனிச் , ப்ரொஃபெஸர் க்கு அணு மருந்து , தொழில்நுட்ப பல்கலைக்கழகம் , அணு மருந்து , உயிரியல் வேதியியல் , பிறப்பு குறைபாடுகள் , பல மைலோமா ,