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Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases
Scientists believe that an unbiased analysis of antibody binding sites would provide significant insights into health and disease states. In this regard, many researchers have utilized programmable phage display libraries to detect novel autoantibodies. Phage display libraries have been used to characterize anti-viral immunity and profile allergen-specific Immunoglobulin E (IgE) antibodies.
Even though protein microarrays are extremely useful for protein research, the high per-assay cost and numerous technical artifacts make them less user-friendly. Technologies such as Nucleic Acid Programmable Protein Array (NAPPA) and single-molecule PCR-linked in vitro expression (SIMPLEX) are effective but not cost-effective. ....

Priyom Bose , Halotag Haloligand , Self Assembly , Nucleic Acid Programmable Protein Array , Using Molecular Indexing , Image Credit , Preprint Graphical Abstract , Parallel Analysis , Translated Open , Molecular Indexing , N Terminal Halotag , Coronavirus Disease Covid 19 , Sars Cov 2 , High Throughput , In Vitro , Nucleic Acid , பிரீயோம் போஸ் , சுய சட்டசபை , படம் கடன் , இணையாக பகுப்பாய்வு , இல் விட்ரோ ,

Zoran Drvenkar's "Sorry" - Words Without Borders

Zoran Drvenkar’s “Sorry”
Knopf, 2011
Rare is the thriller that surpasses the limits of genre fiction. But Zoran Drvenkar’s Sorry is one such book: a thriller on its face, but also a thoughtful study in guilt and innocence, violence and redemption.
Rare is the thriller that surpasses the limits of genre fiction. But Zoran Drvenkar’s
Sorry is one such book: a thriller on its face, but also a thoughtful study in guilt and innocence, violence and redemption. It alternates among the first, second and third persons, with almost each of the eight chapters bifurcating into “After” and “Before” sections. Drvenkar flirts with postmodern forms and high jinks but manages to avoid sounding gimmicky. These narrative inversions are organic to a story that abounds in unexpected turns and keeps the reader exactly as blind as the characters themselves. ....

Vukovarsko Srijemska , Zoran Drvenkar , Shaun Whiteside , Man Who Wasn T , Friedrich Glauser Prize , International Literature , ஷான் வெள்ளைப்பக்கம் , பிரீட்ரிச் கிளாசர் ப்ரைஸ் , சர்வதேச இலக்கியம் ,

Twenty Years of Île en île: A Conversation with Thomas C. Spear

Twenty Years of Île en île: A Conversation with Thomas C. Spear
Thomas C. Spear. Photo credit: Emmanuel J. Duogène.
From 1998 until January 2021, Professor Thomas C. Spear edited Île en île, an extensive virtual archive of literature from French-speaking islands and their diasporas. Although there will no longer be updates or new material, the entire Île en île archive remains accessible online. Today on WWB Daily, Professor Spear speaks with us about the evolution of Île en île over more than two decades and recommends some of his favorite authors in the archive, many of whom have yet to be translated into English. ....

French Guiana , United States , Simone Schwarz Bart , Oswald Durand , Fabienne Pasquet , Maya Kamaty , Chantalt Spitz , Lyonel Trouillot , Emmanuelj Duog , Jacques Stephen Alexis , Jacques Rabemananjara , Thomasc Spear , Marie Vieux Chauvet , Kettly Mars , Atlantic Djerba , Dany Laferri , Nassur Attoumani , Yanick Lahens , Indian Ocean , Gerty Dambury , Professor Thomas , Professor Spear , Saharan Africa , Global South , North Africa , Alfred Alexandre ,

Hindi writer Bhuwaneshwar has been largely forgotten. A new book of his stories revives his work

Hindi writer Bhuwaneshwar has been largely forgotten. A new book of his stories revives his work
‘Alas the human heart’, a short story from ‘Wolves and Other Stories’, Bhuwaneshwar, translated by Saudamini Deo.
A book of Hindi short stories by Bhuwaneshwar.
That little incident now doesn’t seem as sharp and intense in memory’s blurred and sombre shadow. today, when I want to run away from this world of light, laughter and virtue to that ugly dark- ness in which I want to open my eyes with ebullience and insanity, I feel stifled. “Today” means my success, my courage; and the failure and cowardice of those innumerable men and women who competed against me in the race of life. ....

Alif Laila , Books And Ideas , Saudamini Deo , Hindi Literature , Short Stories , அலிஃப் லைலா , புத்தகங்கள் மற்றும் யோசனைகள் , ச Ud தமினி தியோ , இந்தி இலக்கியம் , குறுகிய கதைகள் ,

Researchers develop a genetic patch to prevent hereditary deafness

They can hear well up to about forty years old, but then suddenly deafness strikes people with DFNA9. The cells of the inner ear can no longer reverse the damage caused by a genetic defect in their DNA. ....

Van Wijk , Erwin Van Wijk , Emily Henderson , Southern Netherlands , Molecular Therapy , வேன் விஜக் , அர்‌விந் வேன் விஜக் , எமிலி ஹென்டர்சன் , தெற்கு நெதர்லாந்து , மூலக்கூறு சிகிச்சை ,