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April 09, 2021 One of the first papers to document the rare thrombotic events seen in Austria and Germany involving a form of thrombocytopenia after inoculation with the vaccine jointly developed by the University of Oxford and AstraZeneca has now been published in the New England Journal of Medicine, accompanied by a brief report confirming similar findings in a Norwegian cohort. Taken together the papers show a clear link between this particular vaccine and the ”clotting abnormalities” that have led countries around the world to pause or revise their plans for the use of the Oxford/AstraZeneca product. Critically, say authors, the reports also point the way for definitive testing with widely available tests that would permit affected patients to be swiftly identified and treated, potentially averting serious thrombotic events. ....
February 04, 2021 Patients with cancer, including hematologic, breast, and lung cancer, who present with STEMI fare just as well with primary PCI as those without cancer, according to the results of a new study. While primary PCI is underutilized in this high-risk group, with just half of lung cancer patients, for example, taken to the cath lab for revascularization, researchers found there was no significant difference in the risk of in-hospital major adverse cardiovascular and cerebrovascular events or all-cause mortality based on whether STEMI patients had cancer. “Overall, these findings should provide some reassurance or evidence for operators who might be more cautious and potentially worried about causing harm in this high-risk group,” lead investigator Mohamed O. Mohamed, MBBCh (Keele University/Royal Stoke University Hospital, Stoke-on-Trent, England), told TCTMD. ....