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New drug target valid for breast cancer as well as lymphoma


New drug target valid for breast cancer as well as lymphoma
One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research.
The results provide more justification and rationale for starting the clinical trial in May. It s another exciting stepping stone to finding out if this is going to be a new cancer treatment.
John Mackey, First Author, Professor and Director of Oncology Clinical Trials, Faculty of Medicine & Dentistry, University of Alberta
The drug PCLX-001 is designed to selectively kill cancer cells by targeting enzymes involved in myristoylation, a process key to the cell signaling system that is often defective in cancer cells. The molecule was originally developed by the University of Dundee as a treatment for African sleeping sickness. U of A cell biologist Luc Berthiaume was the first to realize it ....

John Mackey , Luc Berthiaume , Emily Henderson , Cross Cancer Institute In Edmonton , University Of Alberta , Alberta Cancer Foundation , Cure Cancer Foundation , University Of Dundee , Pacylex Pharmaceuticals , Cross Cancer Institute , Cure Cancer , Cancer Treatment , Breast Cancer , Clinical Trial , ஜான் மேக்கி , லூக் பெர்த்தியாம் , எமிலி ஹென்டர்சன் , குறுக்கு புற்றுநோய் நிறுவனம் இல் எட்மண்டன் , பல்கலைக்கழகம் ஆஃப் ஆல்பர்ட்டா , ஆல்பர்ட்டா புற்றுநோய் அடித்தளம் , குணப்படுத்த புற்றுநோய் அடித்தளம் , பல்கலைக்கழகம் ஆஃப் டண்டீ , குறுக்கு புற்றுநோய் நிறுவனம் , குணப்படுத்த புற்றுநோய் , புற்றுநோய் சிகிச்சை , மார்பக புற்றுநோய் ,

FISH technique can be used to probe sperm DNA for chromosomal defects

New Drug Combination Discovered To Treat A Rare Cancer Form


New Drug Combination Discovered To Treat A Rare Cancer Form
by Pooja Shete on 
January 17, 2021 at 12:35 AM
Waldenström macroglobulinemia (WM) is a rare form of lymphoma, which does not have any known cures. It is challenging to these patients as there is only one FDA-approved treatment. The researchers took the novel approach of targeting specific cell proteins that control DNA information using inhibitors. They even used drugs that were effective in reducing the growth of the cancer cells and when combined with a third drug showed greater success in killing the WM cancer cells. This can lead to more effective treatment options. ....

Bet Inhibitors ,