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Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases
Autoimmune diseases, in which the body s own immune system attacks healthy tissue, can be life-threatening and can impact all organs. A research team at the Technical University of Munich (TUM) has now found a possible cause for these self-destructive immune system attacks: a hyperactive RANK protein on the surface of B cells. The research opens the door to new therapeutic possibilities.
The immune system can be a mixed blessing: Usually it is highly effective in protecting the human organism against bacteria, viruses and mycosis and even cancer. But these defense cells can also turn against the body s own tissues and trigger autoimmune diseases, including for example rheumatoid arthritis and systemic lupus erythematosus, an illness involving chronic dermatitis and inflammation of the joints, the nervous system and internal organs or even become cancer cells themselves and dev ....

Maike Buchner , Juergen Ruland , Emily Henderson , Technical University Of Munich , German Research Foundation , Institute Of Clinical Chemistry , Institute For Clinical Chemistry , Technical University , Clinical Chemistry , Research Foundation , Leibniz Prize , Receptor Activator , Autoimmune Disease , Immune System , Lupus Erythematosus , Nervous System , Rheumatoid Arthritis , Systemic Lupus Erythematosus , ஜூர்கன் ருளந்ட் , எமிலி ஹென்டர்சன் , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் முனிச் , ஜெர்மன் ஆராய்ச்சி அடித்தளம் , நிறுவனம் ஆஃப் மருத்துவ வேதியியல் , நிறுவனம் க்கு மருத்துவ வேதியியல் , தொழில்நுட்ப பல்கலைக்கழகம் , மருத்துவ வேதியியல் ,

Teen paints masterpieces to raise funds for medical treatment

Belle pours her heart into her paintings. Photo: Angie Lim
She bends over a canvas, painstakingly bringing colourful masterpieces of flowers and animals to life. Despite suffering from systemic lupus erythematosus (SLE), an autoimmune disease that results in inflammation and tissue damage in the organs, and having to spend much of her life undergoing treatments in the hospital, 13-year-old Belle Chok has a steely determination as she completes her masterpiece which will be sold to raise funds for her medical treatment.
Whenever she is hospitalised at Selayang Hospital, Kuala Lumpur, her father, a plumbing contractor, has to pay thousands of ringgit in medical bills. The medicines that she needs on a daily basis also comes up to RM60 per day (RM1,800 monthly). ....

Kuala Lumpur , Belle Chok , Selayang Hospital , Angie Lim , Acrylic Painting , Chinese New Year , குவாலா லம்பூர் , பெல்லி சோக் , ஆங்கி லிம் , நிதி திரட்டல் , அக்ரிலிக் ஓவியம் , சீன புதியது ஆண்டு ,

More Than 200,000 Americans Have Lupus

More Than 200,000 Americans Have Lupus
By Robert Preidt
HealthDay Reporter
THURSDAY, Jan. 21, 2021 (HealthDay News) Just over 200,000 Americans have the autoimmune disorder lupus, and minority women are at highest risk, according to a new study.
It s the first estimate of how widespread the disease is in the United States. The number comes close to reclassifying lupus as a rare disease, defined as an illness affecting 200,000 Americans or fewer, the researchers said.
Our study potentially redefines systemic lupus erythematosus as a rare disease in the United States and lays the groundwork for where we need to focus our efforts to reduce the burden of this disease on Americans, lead investigator Dr. Peter Izmirly said in a news release from NYU Langone Health in New York City. He s a rheumatologist and associate professor of medicine at the health system. ....

United States , New York , Peter Izmirly , Indian Native Health Service , Langone Health , Healthday News , Indian Native Health , Alaskan Native , Autoimmune Disease , Autoimmune Disorder , Chronic Pain , ஒன்றுபட்டது மாநிலங்களில் , புதியது யார்க் , இந்தியன் பூர்வீகம் ஆரோக்கியம் சேவை , லன்கொனே ஆரோக்கியம் , இந்தியன் பூர்வீகம் ஆரோக்கியம் , அலாஸ்கன் பூர்வீகம் , ஆட்டோ இம்யூன் நோய் , ஆட்டோ இம்யூன் கோளாறு , நாள்பட்ட வலி ,

Study reveals new insights into how UV light triggers kidney inflammation in lupus patients

A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington (UW) and published in the Proceedings of the National Academy of Sciences, reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. ....

Sladjana Skopelja Gardner , Keith Elkon , Emily Henderson , Geisel School Of Medicine At Dartmouth , Geisel School Of Medicine , Proceedings Of The National Academy Sciences , University Of Washington , Geisel School , National Academy , Assistant Professor , Autoimmune Disease , Health Care , Immune System , Kidney Disease , எமிலி ஹென்டர்சன் , கேசெல் பள்ளி ஆஃப் மருந்து இல் டார்ட்மவுத் , கேசெல் பள்ளி ஆஃப் மருந்து , பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் , கேசெல் பள்ளி , தேசிய கலைக்கழகம் , உதவியாளர் ப்ரொஃபெஸர் , ஆட்டோ இம்யூன் நோய் , ஆரோக்கியம் பராமரிப்பு , நோய் எதிர்ப்பு சக்தி அமைப்பு , கிட்நீ நோய் ,

Exposure to Sunlight Worsens Autoimmune Diseases

Exposure to Sunlight Worsens Autoimmune Diseases
by Anjanee Sharma on
January 22, 2021 at 3:42 PM
Autoimmune diseases are those diseases that occur when the immune system attacks its own tissues. Lupus is one such disease and can cause inflammation of the joints, skin, kidneys, blood cells, brain, heart, and lungs.
A study reveals that skin exposure to ultraviolet (UV) light can worsen clinical symptoms in autoimmune diseases such as lupus, an unexpected insight.
Prior research has determined that sunlight exposure can trigger local skin inflammation, systemic flares, and kidney disease in up to 80 percent of lupus patients. The underlying mechanisms that drive this process are yet to be understood. ....

Immune System , Kidney Damage , Ultraviolet Light , Uv Exposure , நோய் எதிர்ப்பு சக்தி அமைப்பு , கிட்நீ சேதம் , ஊவ் நேரிடுவது ,