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Antibodies Deplete Cancer Cells in Mice and Human Cell Lines

Antibodies Deplete Cancer Cells in Mice and Human Cell Lines
by Angela Mohan on
March 2, 2021 at 12:14 PM
Science,
Science Immunology.
Some immunotherapy approaches against cancers rely on common cancer-related mutations to serve as antigens; they instigate an immune response to the cancer.
Although it is one of the most common mutant tumor suppressor genes known in human cancers, the cancer-related p53 tumor suppressor gene has not been successfully targeted via this approach.
In
Science, Emily Han-Chung Hsiue and colleagues successfully engineered a bispecific antibody to reactivate p53. Hsiue et al. first identified a distinct targetable fragment of the mutant tumor suppressor protein and characterized the structural basis for how the fragment is presented to T cells. ....

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Euthanized Central Park Horse Had Genetic Disorder But Activists Claim Neglect Played a Role

Documents of the NYC Department of Health and Mental Hygiene dated March 2019 and October 2019 showed that Aysha was in good health prior to its death. Also included in documents released by the Transport Workers Union are statements from veterinarians Dennis Farrell and Camilo Sierra who respectively examined the horse prior to and following its death.
Farrell and Sierra appeared to confirm that laboratory results led them to believe that PSSM was the cause of the horse s uncontrolled movements.
We want to share these medical records because the carriage folks have always been transparent and open about our horses’ lives and our work together, Christina Hansen, a spokesperson for the carriage horse drivers, said in a news release. ....

Clinton Park , United States , Christina Hansen , Dennis Farrell , City Council , Equine Health , Department Of Health , Uc Davis Center , Workers Union , New York City Central Park , Clinton Park Stables , Polysaccharide Storage Myopathy , Mental Hygiene , Transport Workers Union , Camilo Sierra , New Yorkers , Safe Streets , Director Edita Birnkrant , Central Park , New York , City Amp , Historic Horse Drawn Carriages , Horse Collapse , New York City , கிளின்டன் பூங்கா , ஒன்றுபட்டது மாநிலங்களில் ,

Euthanized Horse Had Genetic Disorder but Activists Claim Neglect Played a Role

Documents of the NYC Department of Health and Mental Hygiene dated March 2019 and October 2019 showed that Aysha was in good health prior to its death. Also included in documents released by the Transport Workers Union are statements from veterinarians Dennis Farrell and Camilo Sierra who respectively examined the horse prior to and following its death.
Farrell and Sierra appeared to confirm that laboratory results led them to believe that PSSM was the cause of the horse s uncontrolled movements.
We want to share these medical records because the carriage folks have always been transparent and open about our horses’ lives and our work together, Christina Hansen, a spokesperson for the carriage horse drivers, said in a news release. ....

Christina Hansen , Dennis Farrell , City Council , Equine Health , Department Of Health , Uc Davis Center , Workers Union , New York City , Central Park , Clinton Park Stables , Polysaccharide Storage Myopathy , Mental Hygiene , Transport Workers Union , Camilo Sierra , New Yorkers , Safe Streets , Director Edita Birnkrant , New York , City Amp , Historic Horse Drawn Carriages , Horse Collapse , கிறிஸ்டினா ஹேன்சன் , டென்னிஸ் ஃப்யாரெல் , நகரம் சபை , குதிரை ஆரோக்கியம் , துறை ஆஃப் ஆரோக்கியம் ,

Archaeologists find intact ceremonial chariot near Pompeii buried in ash for 2,000 years

Archaeologists find intact ceremonial chariot near Pompeii buried in ash for 2,000 years
Published March 1
A view of a chariot, with its iron elements, bronze decorations and mineralized wooden remains, that was found in Civita Giuliana, north of Pompeii. Officials at the Pompeii archaeological site near Naples on Saturday, Feb. 27, 2021, announced the first-ever discovery of an intact ceremonial chariot, one of several important discoveries made in the same area outside the park following an investigation into an illegal dig. (Parco Archeologico di Pompei via AP)
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MILAN Officials at the Pompeii archaeological site in Italy announced Saturday the discovery of an intact ceremonial chariot, one of several important discoveries made in the same area outside the park near Naples following an investigation into an illegal dig. ....

Mediterranean Sea , Oceans General , Civita Giuliana , Civita Giulian , Archaeological Park , Mount Vesuvius , Parco Archeologico , மத்திய தரைக்கடல் கடல் , பெருங்கடல்கள் ஜநரல் , சிவில் கியுலியானா , தொல்பொருள் பூங்கா , ஏற்ற வெஸ்யூவீயஸ் ,

Pompeii archaeologists find intact ceremonial chariot at site of illegal dig

Officials at the Pompeii archaeological site in Italy announce the discovery of an intact ceremonial chariot, one of several important discoveries made in the same area outside the historical park following an investigation into an illegal dig. ....

Mediterranean Sea , Oceans General , Civita Giulian , Archaeological Park , Mount Vesuvius , மத்திய தரைக்கடல் கடல் , பெருங்கடல்கள் ஜநரல் , தொல்பொருள் பூங்கா , ஏற்ற வெஸ்யூவீயஸ் ,