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Mini-antibodies efficiently block SARS-CoV-2 virus


Mini-antibodies efficiently block SARS-CoV-2 virus
Göttingen researchers have developed mini-antibodies that efficiently block the coronavirus SARS-CoV-2 and its dangerous new variants. These so-called nanobodies bind and neutralize the virus up to 1000 times better than previously developed mini-antibodies. In addition, the scientists optimized their mini-antibodies for stability and resistance to extreme heat. This unique combination makes them promising agents to treat COVID-19. Since nanobodies can be produced at low costs in large quantities, they could meet the global demand for COVID-19 therapeutics. The new nanobodies are currently in preparation for clinical trials.
Antibodies help our immune system to fend off pathogens. For example, the molecules attach to viruses and neutralize them so that they can no longer infect cells. Antibodies can also be produced industrially and administered to acutely ill patients. They then act like drugs, relieving symptoms and sho ....

Holm Keller , Antje Dickmanns , Max Planck , Metin Aksu , Matthias Dobbelstein , Emily Henderson , Kim Stegmann , Institute Of Molecular Oncology , University Medical Center , Enup Foundation , Max Planck Institute , Johannes Bange Lead Discovery Center , Biophysical Chemistry , Dieter Link , Max Planck Innovation , Johannes Bange , Lead Discovery Center , ஹோல்ம் கெல்லரர் , எமிலி ஹென்டர்சன் , நிறுவனம் ஆஃப் மூலக்கூறு புற்றுநோயியல் , பல்கலைக்கழகம் மருத்துவ மையம் , உயிர் இயற்பியல் வேதியியல் , டயட்டர் இணைப்பு , வழி நடத்து கண்டுபிடிப்பு மையம் ,

New drug inhibits growth of cancer cells


New drug inhibits growth of cancer cells
ANI |
Updated: Dec 23, 2020 12:21 IST
Washington [US], December 23 (ANI): A recent study has found a newly developed compound that starves cancer cells by attacking their power plants - the so-called mitochondria.
The new compound prevents the genetic information within mitochondria from being read.
Researchers from the Max Planck Institute for Biology of Ageing in Cologne, the Karolinska Institute in Stockholm, and the University of Gothenburg report in their study that this compound could be used as a potential anti-tumour drug in the future; not only in mice but also in human patients.
Mitochondria provide our cells with energy and cellular building blocks necessary for normal tissue and organ function. For a long time, the growth of cancer cells was assumed to be independent of mitochondrial function. ....

United States , Vastra Gotalands Lan , Nils Goran Larsson , Nina Bonekamp , Karolinska Institute , University Of Gothenburg , Discovery Center , Max Planck Institute , Lead Discovery Center , Max Planck Innovation , Biophysical Chemistry , ஒன்றுபட்டது மாநிலங்களில் , நில்ஸ் கோரான் லார்சன் , பல்கலைக்கழகம் ஆஃப் கோடெந்ப்ர்க் , கண்டுபிடிப்பு மையம் , வழி நடத்து கண்டுபிடிப்பு மையம் , உயிர் இயற்பியல் வேதியியல் ,