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Trevena Announces First Patien - GuruFocus.com

Confirm
TRV027 will be dosed in ~300 patients in nationwide trial led by Vanderbilt University Medical Center (VUMC)
CHESTERBROOK, Pa., July 26, 2021 (GLOBE NEWSWIRE)
Trevena, Inc. ( TRVN), a biopharmaceutical company focused on the development and commercialization of novel medicines for patients with central nervous system (CNS) disorders, today announced that the first COVID-19 patient has been enrolled in the NIH-funded ACTIV-4 Host Tissue (Accelerating COVID-19 Therapeutic Interventions and Vaccines) trial.
“There is no one solution to end COVID-19, and we are honored to play a role in the global effort to overcome this pandemic and mitigate its long-term impact on our communities,” said Carrie Bourdow, President and CEO of Trevena. “I am excited that patients are now being enrolled in this study and that TRV027 is the one of the first active treatment arms available for patient randomization.” ....

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Trevena Announces First Patient Enrolled in NIH-Funded

Trevena Announces First Patient Enrolled in NIH-Funded
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Constant Therapeutics TXA127 For COVID-19 To Enter NIH-Funded Clinical Trial At 60 Sites Around The U.S.

/PRNewswire/ As the focus on the COVID-19 pandemic shifts to raising the number of vaccinated people around the world, U.S. researchers, funded by the NIH,. ....

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Trevena Announces TRV027 Selected by NIH-Funded ACTIV Initiative For COVID-19 Trial

Trevena Announces TRV027 Selected by NIH-Funded ACTIV Initiative For COVID-19 Trial
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VUMC to lead national study to treat severe COVID complications

by Bill Snyder
The Vanderbilt Institute for Clinical and Translational Research (VICTR) has been awarded a major federal grant to lead a national trial of treatments targeting the Renin Angiotensin Aldosterone System (RAAS) in patients hospitalized with COVID-19.
Comprised of the hormones renin, angiotensin and aldosterone, RAAS is essential for the regulation of blood pressure and fluid balance. SARS-CoV-2, the virus that causes COVID-19, can disrupt this system, resulting in life-threatening complications, including pulmonary edema, thromboembolic complications and severe cardiac injury.
Sean Collins, MD, MSc, professor of Emergency Medicine at Vanderbilt University Medical Center, who has deep expertise in emergency care and RAAS, will lead the trial, which will test whether drugs targeting RAAS can prevent the vascular, fibrotic and inflammatory consequences of severe COVID-19 disease. ....

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