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Vitamin D deficiency does not increase risk of type 1 diabetes


Credit: Michele Blackwell on Unsplash, CC0
Genetically determined vitamin D levels do not have a large effect on risk of type 1 diabetes in Europeans, according to a study published 25th February 2021 in the open-access journal
PLOS Medicine by Despoina Manousaki from the CHU Sainte Justine and the University of Montreal, Canada and colleagues.
Type 1 diabetes is a relatively common autoimmune disease that inflicts substantial lifelong illness and significant economic burden. Its incidence is increasing worldwide, and there are no known interventions that can be used to prevent the disease. Vitamin D deficiency has been associated with type 1 diabetes in observational studies, but evidence of a causal effect from randomized controlled trials is lacking. In the new study, the researchers used a Mendelian randomization design to test whether genetically decreased vitamin D levels increase risk of type 1 diabetes. Mendelian randomization is a method of using measured var ....

Sainte Justine , Despoina Manousaki , Research Council Integrative Epidemiology Unit , Biomedical Research Centre At University Hospitals Bristol , Research Article , National Multiple Sclerosis Society , University Of Montreal , Wellcome Trust Investigator , Sclerosis Society Of Canada , Clinician Scientist Development Award , Integrative Cancer Epidemiology Programme , Canadian Institute Of Health Research , University Of Bristol , Canadian Institute , Health Research , Scientist Development Award , Multiple Sclerosis Society , Avon Longitudinal Study , Research Centre , University Hospitals Bristol , Epidemiology Unit , Cancer Epidemiology Programme , Deerfield Capital , Editorial Board , புனிதர் ஜஸ்டின் , ஆராய்ச்சி சபை ஒருங்கிணைந்த தொற்றுநோய் அலகு ,