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Crinetics Pharmaceuticals Reports First Quarter 2021 Financial Results and Provides Corporate Update


Crinetics Pharmaceuticals Reports First Quarter 2021 Financial Results and Provides Corporate Update
Paltusotine Phase 3 PATHFNDR program in acromegaly initiated in 2Q 2021
Phase 1 data for CRN04894 and CRN04777 expected in mid-2021
SAN DIEGO, May 06, 2021 (GLOBE NEWSWIRE)
Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors, today announced financial results for the first quarter ended March 31, 2021 and provided a corporate update.
“In the first quarter we achieved key clinical and regulatory milestones across our pipeline,” said
Scott Struthers, Ph.D., Founder and Chief Executive Officer of Crinetics. “Based on our interactions with the FDA and other regulators, we developed a robust Phase 3 program for paltusotine that is designed to support its approval for all acromega ....

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Sonance Foundation Gifts $1,500 to Family Assistance Ministries


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A gift donation of $1,500 will Support Gilchrist House to Help Individuals in Transition. (FAM Ministries photo.)
SAN CLEMENTE, CA In an annual tradition, San Clemente-based Sonance co-founders, Scott Struthers & Geoff Spencer, along with Struthers & Amber Ringstad, donated $1,500 to the Gilchrist House.
At Sonance, we do everything as a team, said Ari Supran, Chief Executive Officer of Sonance. Not just at work, but when we volunteer. Whether it s cleaning up our local beaches, helping kids at the local Boys & Girls Club, or assembling bags of food for distribution at Family Assistance Ministries, we are at our best when we are serving others. ....

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Crinetics Pharmaceuticals Lead ACTH Antagonist for Congenital Adrenal Hyperplasia and Cushing's Disease (CRN04894) Advances into Phase 1 Study


Published: Feb 04, 2021
SAN DIEGO, Feb. 04, 2021 (GLOBE NEWSWIRE) Crinetics Pharmaceuticals Inc.. (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors, today announced that CRN04894, the company’s lead adrenocorticotropic hormone (ACTH) antagonist for the treatment of diseases associated with excess ACTH such as Cushing’s disease and congenital adrenal hyperplasia (CAH), has advanced into the clinic. Based on encouraging preclinical results, Crinetics has initiated a double-blind, randomized, placebo-controlled Phase 1 study of this orally administered, nonpeptide small molecule drug candidate in healthy volunteers. This study will assess the safety and tolerability of single and multiple doses of CRN04894 and will measure the effect of CRN04894 on suppression of cortisol, cortisol precursors, and adrenal androgens following ....

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