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Vascular Smooth Muscle Cells via JNK/c-JUN Pathway


Purpose: The deposition of hydroxyapatite (HAp) crystals plays an important role in the development of vascular calcification (VC). This study aimed to demonstrate the effects of nanosized HAp (nHAp) on vascular smooth muscle cells (VSMCs) and VC progression.
Methods: Transmission electron microscopy (TEM) was used to examine cellular uptake of nHAp. Cell viability was determined using CCK-8 assay kit. Mitochondrial impairment and reactive oxygen species were detected by TEM and fluorescence dye staining, respectively. Cell apoptosis was detected by Western blot analysis and Annexin V staining. Mouse model of VC was built via applying nHAp on the surface of abdominal aorta. Calcification was visualized by Alizarin red and von Kossa staining. ....

Minato Ku , United States , United Kingdom , Hexadecyl Pyridinium , Annexinv Annexin , Laboratory Animals , United States National Institutes Of Health , Program Graph , Second Affiliated Hospital Of Zhejiang University , Alizarin Red Solarbio Life Sciences , Slac Laboratory Animal , Ethics Review Committee , Aladdin Biochemical Technology Company Shanghai , Care Committee Of Zhejiang University , Cell Signaling Technology , Kit Solarbio Life Sciences , Modified Eagle , Aladdin Biochemical Technology Company , Cell Counting , Beyotime Biotechnology , Reactive Oxygen Species , Electron Microscopy , Hitachi Model , Mitochondrial Membrane Potential , Alkaline Phosphatase , San Jose ,

$2.8 Billion Worldwide Optical Microscopes Industry to 2027 - Impact of COVID-19 on the Market


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The publisher brings years of research experience to the 9th edition of this report. The 287-page report presents concise insights into how the pandemic has impacted production and the buy side for 2020 and 2021. A short-term phased recovery by key geography is also addressed.
Global Optical Microscopes Market to Reach $3.9 Billion by 2027
Amid the COVID-19 crisis, the global market for Optical Microscopes estimated at US$2.8 Billion in the year 2020, is projected to reach a revised size of US$3.9 Billion by 2027, growing at a CAGR of 4.9% over the analysis period 2020-2027.
Digital Microscopes, one of the segments analyzed in the report, is projected to record a 5.1% CAGR and reach US$1.2 Billion by the end of the analysis period. After an early analysis of the business implications of the pandemic and its induced economic crisis, growth in the Stereo Microscope segment is readjusted ....

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