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PD-L1 Inhibitor Thwarts Recurrence in Early Lung Cancer


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Patients with early-stage non-small cell lung cancer (NSCLC) lived significantly longer without disease recurrence if they received atezolizumab (Tecentriq) after surgery and chemotherapy, a large randomized trial showed.
Median disease-free survival (DFS) had yet to be reached after a median follow-up of 32.8 months, but the results met criteria for statistical significance, showing a 34% reduction in the hazard ratio for patients with stage II-IIIa disease and PD-L1 tumor cell expression ≥1%, said Heather Wakelee, MD, of Stanford University Medical Center in California, during a press briefing in advance of the virtual American Society of Clinical Oncology (ASCO) annual meeting.
An analysis limited to patients with stage II-IIIa disease (irrespective of PD-L1 expression) showed they were significantly more likely to be alive and disease free if they received atezolizumab instead of best supportive care (BSC) after chemotherapy. An intention-to-t ....

Stanford University , United States , Julie Gralow , Heather Wakelee , Charles Bankhead , University Of Washington , American Society Of Clinical Oncology , Stanford University Medical Center , American Society , Clinical Oncology , Medical Officer , Executive Vice President Julie Gralow , Medpage Today , ஸ்டான்போர்ட் பல்கலைக்கழகம் , ஒன்றுபட்டது மாநிலங்களில் , ஹீத்தர் விழித்தெழு , சார்லஸ் வங்கித் தலை , பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் , அமெரிக்கன் சமூகம் ஆஃப் மருத்துவ புற்றுநோயியல் , ஸ்டான்போர்ட் பல்கலைக்கழகம் மருத்துவ மையம் , அமெரிக்கன் சமூகம் , மருத்துவ புற்றுநோயியல் , மருத்துவ அதிகாரி ,

Researchers examine the connection between lung cancer and COVID-19


Researchers examine the connection between lung cancer and COVID-19
On February 27, 2020, the flagship journal of the International Association for the Study of Lung Cancer, the
Journal of Thoracic Oncology, published a case study that described two patients from Wuhan, China who recently underwent lung lobectomies for adenocarcinoma and were retrospectively found to have had COVID-19 at the time of surgery.
Eleven months later, the lung cancer research community gathered virtually at the IASLC 2020 World Conference on Lung Cancer Singapore to share a number of research findings examining the intersection of COVID-19 and lung cancer. Researchers from a variety of countries participated in a press briefing to examine the connection between lung cancer and COVID-19. ....

United States , City Of , United Kingdom , Comunidad Autonoma De Cataluna , Umit Tapan , Domenico Galetta , Ivy Elkins , Emily Henderson , Matthew Peters , Stephanie Wynne , Heather Wakelee , Roxana Reyes , Jessica Selig , Division Of Medical Oncology At Stanford University , Boston Medical Center , Guy Cancer Centre , Oncology Institute , Thoracic Oncology Group , Global Lung Cancer Coalition , Lungevity Foundation , Stanford Cancer Institute , Editorial Group , International Association , Lung Cancer , Thoracic Oncology , Lung Cancer Singapore ,