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Existing drug may be effective in treating SARS-CoV-2


Existing drug may be effective in treating SARS-CoV-2
Scientists from the University of Chicago have found that the drug masitinib may be effective in treating COVID-19.
The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2, the virus that causes COVID-19, in human cell cultures and in a mouse model, leading to much lower viral loads.
X-ray crystallography gave us a strong indication of how this drug works, and we became confident that it has a chance to work in humans.
Nir Drayman, University of Chicago ....

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Jeff Rankin: Kirkwood native preserved her father's banking legacy


Jeff Rankin: Kirkwood native preserved her father’s banking legacy
Jeff Rankin
The Rankin File
Growing up in Monmouth during the 1970s, one of the interesting landmarks I recall was a circular brick fountain in front of the National Bank of Monmouth’s Colonial Drive-In on East Broadway. It was particularly memorable because of a recurring nighttime prank by members of a Monmouth College sorority, who would drop a Salvo laundry tablet into the basin and by morning the fountain would be overflowing with suds.
Affixed to the masonry was a bronze plaque, announcing that it was the Myra Tubbs Ricketts Memorial Fountain. I always chuckled at that name, especially having no idea who Mrs. Ricketts was or why a fountain would be named for her. A few years later, however, when I became an employee of the National Bank, I would learn all about the Tubbs and Ricketts families, and about Myra’s prominent role in the bank’s history. ....

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