The mosquito-borne deadly dengue virus that infects about 400 million people globally every year—especially in the tropic and sub-tropic regions of the world—is undergoing changes that are helping it evade vaccines and therapeutics, according to a study. The research, published in the journal PLOS Pathogens, notes that one of the strains of the virus, DENV2 has smooth spherical surface particles while growing at the carrier mosquito’s physiological temperature of 29 degrees Celsius.