Page 34 - Cell Stem News Today

2Department of Microbiology, Linyi Center for Disease Control and Prevention, Linyi, China 3Department of Immunology, School of Basic Medicine, Qingdao University, Qingdao, China 4Department of Infectious Disease, The Affiliated Hospital of Qingdao University, Qingdao, China 5Department of Medical Education, Qingdao Chest Hospital, Qingdao, China 6Department of Infectious Disease, Qingdao Centre for Disease Control and Prevention, Qingdao Institute of Prevention Medicine, Qingdao, China 7Instit...

More than thirty years after discovering Leber’s hereditary optic neuropathy (LHON) as the first maternally inherited disease associated with homoplasmic mtDNA mutations, we still struggle to achieve effective therapies. LHON is characterized by selective degeneration of retinal ganglion cells (RGCs) and is the most frequent mitochondrial disease, which leads to blindness young people, in particular males. Despite the causative mutations are present in all tissues, yet only a specific cell typ...

One of the pioneers of mRNA technology - Luigi Warren

Alzheimer’s Deficits in Neurogenesis and Memory Lessened by Small Molecule Alzheimers disease. [National Institute on Aging/National Institutes of Health] May 26, 2021 Share Brains devastated by Alzheimer’s disease (AD) can be “rejuvenated” by restoring the expression of a microRNA molecule, report scientists based at the Leuven Brain Institute and the Netherlands Institute for Neuroscience (NIN). The molecule, miR-132, is one of the most consistently downregulated microRNAs...

A team of US researchers has, in an alarming study, found direct evidence that Covid-19 can infect cells in the eye.

Covid-19 can infect cells in eye: Study SARS-CoV-2 New York– A team of US researchers has, in an alarming study, found direct evidence that Covid-19 can infect cells in the eye. SARS-CoV-2, which causes Covid-19, is thought to transmit and begin infection in the upper respiratory tract. For this reason, the use of face masks has been recommended for the general public. However, the new study by the Mount Sinai Hospital researchers found that cells in the eye can be directly infected by SARS-C...

Machine learning approach helps study human hypothalamus at the single-cell level Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions such as the cortex and the midbrain, researchers at the Perelman School of Medicine at the University of Pennsylvania have generated the first organoids of the arcuate nucleus (ARC), an essential structure in the hypothalamus that s...

Date Time Penn Researchers Use Arcuate Organoids to Study Development and Disease of Hypothalamus A 70 day ARCO generated from control human iPSC line immunostained with nuclei marker DAPI (white), mature neuron marker NeuN (cyan) and immature neuron marker DCX (green). Image provided by Wei-Kai Huang and Sam Wong. PHILADELPHIA- Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model differe...

Credit: Tel Aviv University Using Zebrafish, researchers from the School of Neurobiology, Biochemistry and Biophysics at the Faculty of Life Sciences of Tel Aviv University have developed an advanced simulation of a key process in the brain - the activation of the stem cells responsible for generating neurons. The simulation revealed that the process, which until today was considered to be random, is in fact coordinated, thereby ensuring the normal production of neurons in the brain. According ...

 E-Mail PHILADELPHIA-- Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions such as the cortex and the midbrain, researchers at the Perelman School of Medicine at the University of Pennsylvania have generated the first organoids of the arcuate nucleus (ARC), an essential structure in the hypothalamus that sends signals of hunger and feeling full. This part of the ...