Page 13 - Confidence Interval News Today

A meta-analysis of trials examining use of preoperative iron infusions suggests use could reduce need for blood transfusions by 33% among patients undergoing colorectal surgery.

A trial randomizing brain-dead donor hearts to levothyroxine administration or saline has returned results challenging conventional wisdom on the topic, with data indicating thyroid hormone administration may provide no significant benefit.

An analysis of data from the Veterans Health Administration provides insight into disparities in the rates of endoscopy or colonoscopy among patients with iron deficiency anemia or hematochezia.

Data from a 24-week, prospective trial conducted at a hospital in China provide insight into the effects of roxadustat on iron metabolism relative to use of ESAs in patients using peritoneal dialysis.

A new analysis of Google search results provides perspective into the readability and quality of educational materials available online related to iron deficiency anemia.

1. In this observational study, patients in high remote patient monitoring (RPM) practices had better hypertension outcomes than those at matched low-RPM practices. 2. Patients in high-RPM practices had more primary care physician outpatient visits and total hypertension-related spending. Evidence Rating Level: 2 (Good) Study Rundown: RPM is a healthcare delivery method where clinicians monitor

1. In this randomized controlled trial, the combination of vancomycin with cefazolin was not superior to surgical antimicrobial prophylaxis with cefazolin alone in patients undergoing arthroplasty. 2. Prophylaxis with vancomycin and cefazolin was associated with an increased risk of hypersensitivity reactions and decreased risk of acute kidney injury (AKI) compared to cefazolin alone. Evidence Rating

1. In these two randomized parallel-group trials, the use of gantenerumab did not lead to slower cognitive decline over 116 weeks among persons with early symptomatic Alzheimer’s disease compared to placebo. 2. After 116 weeks, gantenerumab was associated with lower amyloid plaque burden than the placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: The accumulation

1. In this randomized controlled trial, universal decolonization with topical antiseptics significantly reduced the risks of hospitalization due to infection among nursing home residents as compared to routine care. 2. The number needed to treat (NNT) was 9.7 to prevent one hospitalization due to infection in the nursing home setting. Evidence Rating Level: 2 (Good)

A retrospective analysis of more than 1 million hospitalizations provides insight into the impact of hepatitis C virus infection and cirrhosis on mortality risk in patients hospitalized with COVID-19.