Page 31 - Confidence Interval News Today

1. In this case-crossover study, consumption of caffeinated coffee was associated with fewer minutes of sleep per night and increased levels of daily activity. 2. Consumption of caffeinated coffee did not have a significant association with rates of premature daily atrial contractions. Evidence Rating Level: 2 (Good) Study Rundown: Despite being one of the most

1. In older adults with treatment-resistant depression, aripiprazole-augmentation significantly improved psychological outcomes compared to bupropion-augmentation or switching to bupropion. 2. In older adults with treatment-resistant depression, bupropion-augmentation was associated with a greater risk for falls than aripiprazole-augmentation. Evidence Rating Level: 1 (Excellent) Study Rundown: Major depressive disorder (MDD) is a common condition among older adults

1. In this retrospective cohort study, 68% of female patients with cardiac arrest during their delivery survived until hospital discharge. 2. The most common co-occurring diagnosis was acute respiratory distress syndrome. Evidence Rating Level: 2 (Good) Study Rundown: Cardiac arrest in pregnant adults is uncommon. However, it is associated with severe morbidity. Based on the

The Quality Assurance (QA) requirements for Continuous Emissions Monitoring Systems (CEMS), also known as Automated Measuring Systems (AMS), are specified in the CEN standard EN 14181 which defines three Quality Assurance Levels - QAL1 (certification), QAL2 (calibration) and QAL3 (control). Click to read more...

1. In asymptomatic patients, subclinical coronary atherosclerosis was associated with an eight-fold elevated risk for myocardial infarction (MI). 2. Patients with obstructive and extensive subclinical coronary atherosclerosis had the highest risk of MI. Evidence Rating Level: 1 (Excellent) Study Rundown: Subclinical coronary atherosclerosis can precede ischemic heart disease and evolve at an early age, many

1. In preclinical studies, inaxaplin selectively inhibited apolipoprotein L1 (APOL1) in vitro and reduced proteinuria in a APOL1 G2-homologous transgenic mouse model of proteinuric kidney disease. 2. In a following phase 2a clinical study, 13 participants treated with inaxaplin had a significant reduction in urinary protein-to-creatinine ratio at week 13. Evidence Rating Level: 3 (Average)

1. In this randomized controlled trial, among patients with recurrent kidney stones, hydrochlorothiazide did not alter the risk of symptomatic or radiographic stone recurrence. 2. Hydrochlorothiazide was associated with an increased risk of adverse events as compared to placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Kidney stones are a common medical condition. In many patients, these

1. In this retrospective cohort study, a greater volume of coronavirus 2019 (COVID-19) testing of staff members in skilled nursing facilities reduced the incidence of COVID-19 cases and deaths. 2. In the data subset after vaccines became available, the volume of COVID-19 testing of staff members in skills nursing facilities was not associated with incidence

Data to be featured in proffered paper oral session at ELCC 2023 show Opdivo and chemotherapy administered before surgery reduced the risk of disease recurrence, progression or death by 32% after... | March 30, 2023

Data to be featured in proffered paper oral session at ELCC 2023 show Opdivo and chemotherapy administered before surgery reduced the risk of disease recurrence, progression or death by 32% after three