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Molnupiravir and nirmatrelvir-ritonavir reduce COVID-19 mortality in hospitalized patients

1. In this trial emulation study, molnupiravir and nirmatrelvir-ritonavir reduced all-cause mortality in vaccinated and unvaccinated hospitalized patients with coronavirus disease 2019 (COVID-19). 2. Molnupiravir and nirmatrelvir-ritonavir did not cause any significant reduction in intensive care unit (ICU) admissions or need for ventilatory support. Evidence Rating Level: 1 (Excellent) Study Rundown: Molnupiravir and nirmatrelvir-ritonavir have
United States Minute Medicine Inc Centre For Health Protection Of The Government Large Us Health System Drug Administration Rating Level

72- and 36-hour fever prevention post-cardiac arrest equivalent in preventing mortality

1. In this randomized controlled trial, there was no significant difference in mortality between participants who received fever prevention for 36 versus 72 hours after cardiac arrest. 2. There was no significant difference in cognitive assessment or disability between participants who received fever prevention for 36 versus 72 hours at three months. Evidence Rating Level:
Minute Medicine Inc Rating Level Cerebral Performance Category Montreal Cognitive Assessment Confidence Interval Cardiopulmonary Resuscitation Cpr

Pfizer Announces Positive TALZENNA® and XTANDI® Combination Data from Phase 3 TALAPRO-2 Study

Pfizer (NYSE: PFE) announced today positive results from the Phase 3 TALAPRO-2 study of TALZENNA® (talazoparib), an oral poly ADP-ribose polymerase (PARP) inhibitor, in combination with XTANDI® (enzalutamide), demonstrating a statistically significant and clinically meaningful improvement in radiographic ...
United States Exchange Commission European Medicines Agency Drug Administration Lab Abnormalities Medivation Inc

Adjuvant Opdivo (nivolumab) Continues to Provide Significant, Durable Clinical Benefits for Patients

Three-year median follow-up data demonstrate significantly improved disease-free survival, non-urothelial tract recurrence-free survival, distant metastasis-free survival and second progression-free survival with adjuvant Opdivo compared to placeboRandomized patients who received Opdivo after radical surgery remaine...
United States Dana Walker Matthewd Galsky Company Opdivo American Society Of Clinical Oncology Tisch Cancer Institute

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Opdivo® (nivolumab) in Combination with CABOMETYX® (cabozantinib) Shows Durable Survival with Over T

Data to be featured at ASCO GU 2023 demonstrate continued overall survival, progression-free survival and objective response rate benefits with Opdivo in combination with CABOMETYX compared to sunitinib, regardless of IMDC risk scoreThese three-year data โ€“ with a median follow-up of 44 months โ€“ from CheckMate -9ER r...
United States Dana Walker Claire Mcconnaughey Mauricio Burotto Susan Hubbard Vickil Goodman

A Buddhist AI – "The DUDE" – Explains the Eight Steps of Hybrid Multimodal Document Review with Help from a Human Lawyer | EDRM - Electronic Discovery Reference Model

Written by Chat GPT 3.5, partly in โ€œComic Hipster Styleโ€ with Ralph Losey - Losey to Chat: โ€œUse a comedic hipster writing style to explain my eight steps of electronic document review.โ€...
Ralph Losey Discovery Reference Model Eightfold Doc Review Path Dude Bowls Over Losey Doc Review Hipster Style Humor Language

BioArctic's partner Eisai submits marketing authorization application for lecanemab as treatment for early Alzheimer's disease in Japan

BioArctic's partner Eisai submits marketing authorization application for lecanemab as treatment for early Alzheimer's disease in Japan - read this article along with other careers information, tips and advice on BioSpace
Uppsala Lan Oskar Bosson Uppsala University Vp Communications National Institutes Of Health National Institute On

BioArctic's partner Eisai submits marketing authorization application for lecanemab as treatment for early Alzheimer's disease in Japan

STOCKHOLM, Jan. 16, 2023 /PRNewswire/ -- BioArctic AB's (publ) (NASDAQ Stockholm: BIOA B) partner Eisai announced today that Eisai has submitted a marketing authorization application for lecanemab
Uppsala Lan Oskar Bosson Uppsala University Vp Communications National Institutes Of Health National Institute On

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