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Fundamental mechanism discovered that fine-tunes gene expression & is disrupted in cancer

Credit: The Wistar Institute PHILADELPHIA and MELBOURNE, Australia -- (May. 17, 2021) -- A team of scientists from The Wistar Institute in Philadelphia and the Peter MacCallum Cancer Center in Melbourne, Australia, discovered a new checkpoint mechanism that fine-tunes gene transcription. As reported in a study published in Cell, a component of the Integrator protein complex tethers the protein phosphatase 2A (PP2A) to the site of transcription allowing it to stop the activity of the RNA polyme...
New York United States Dana Farber Cancer Institute New South Wales Benjamin Blyth Otto Kauko

PCR Technologies Market by Technology, Product, Application, End-user and Region - Global Forecast t

Search jobs PCR Technologies Market by Technology, Product, Application, End-user and Region - Global Forecast to 2025 - ResearchAndMarkets.com ResearchAndMarkets.coms offering. The global PCR technologies market is projected to reach USD 9.8 billion by 2025 from USD 7.2 billion in 2020, at a CAGR of 6.3% from 2020 to 2025. The rising incidence of infectious diseases and genetic disorders across the world has spurred the demand for better and faster diagnostic tests. Th...
United States Laura Wood Agilent Technologies Inc Roche Ltd Office Hours Call E St Office Hours Call

COVID19's cytokine storm ushers in a local complement storm in the lungs

COVID19s cytokine storm ushers in a local complement storm in the lungs A new study published in the journal Science Immunology analyzed lung epithelial cells from patients infected with COVID-19 and found the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces the complement system as a dangerous weapon for viral infection. The complement system is an extension of the innate immune system to recognize pathogens and remove them. Prior research has shown a correlation between s...
Jocelyn Solis Moreira Jocelyn Solis Moreiraapr Science Immunology Corona Virus Coronavirus Disease Covid 19 Gene Expression

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Ruchira Papers allots 28.80 lakh convertible warrants

To promoters/ promoter group entitiesRuchira Papers has allotted 28.80 lakh convertible warrants at a price of Rs 62 per warrant to promoters/ promoter group entities, entitling them for the subscription of equivalent number of equity shares of face value Rs. 10/- each (at a premium of Rs. 52 per share) as per the relevant provisions of the SEBI ICDR Regulations, 2018. Powered by Capital Market - Live News (This story has not been edited by Business Standard staff and is auto-generated from a s...
Ruchira Papers Capital Market Gene Expression ருச்சிரா ஆவணங்கள் மூலதனம் சந்தை கீந் வெளிப்பாடு

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells. SARS-CoV-2 is the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic that continues to sweep the globe posing a threat to global public health and the worldwide economy. Marsha Rosner from the University of ...
United States University Of Chicago Marsha Rosner Sally Robertson Drug Administration University Of Chicago Medicine

RNA editing protein ADAR1 protects telomeres and supports proliferation in cancer cells

Credit: The Wistar Institute PHILADELPHIA -- (March 12, 2021) -- Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is required for continued proliferation of cancer cells. These findings, reported in Nature Communications, reveal an additional oncogenic function of ADAR1 and reaffirm its potential as a therapeutic target in cancer. The lab of Kaz...
United States Yusuke Shiromoto Moeko Minakuchi Masayuki Sakurai Kentaro Ariyoshi Kazuko Nishikura

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