Page 23 - Gene Expression News Today

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2 Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respir...

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.

New partnership to develop test for predicting disease course in pediatric Crohns patients The Crohns & Colitis Foundation, the leading non-profit organization focused on both research and patient support for inflammatory bowel disease (IBD), has entered into a partnership with LifeArc, an independent medical research charity that advances translation of early science into health care treatments or diagnostics, to potentially develop the first clinical lab test to predict disease course in pedi...

Tue, 01/26/2021 LAWRENCE — This spring, 41 KU students will receive an Undergraduate Research Award. UGRA recipients are awarded a $1,000 scholarship as they work on mentored research and creative projects.   Students apply for UGRAs by writing a four-page research proposal under the guidance of a mentor. Faculty reviewers evaluate the applications based on the merit of the applicants proposal and a recommendation from the mentor.   “Undergraduate research allows students to ap...

New Method Helps Design Treatments For Deadly Cancers – Gliomas by Karishma Abhishek on  January 23, 2021 at 2:21 PM New method termed as transcriptomic profile (the number of copies of each gene in a cell) of the tumor helps recognize some of the most serious forms of the tumors - Gliomas as per the scientists at Medical College of Georgia reported in the journal Scientific Reports. Gliomas are the common type of brain tumor in adults that affects the support cells of n...

Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in Cancer Cell.

Credit: The Wistar Institute PHILADELPHIA -- (Jan. 21, 2021) -- Researchers at The Wistar Institute have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBVs ability to transform human cells and cause cancer. Published in Cell, this study provides new indications for inhibiting EBNA1 function, opening up fresh avenues for development of therapies to treat EBV-associated cancers. EBV establishes life-long, latent infection in B lymphocyte...

Research finds new evidence about the mechanisms controlling skin repair and regeneration As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal. Skins barrier function gives it the unique ability to fight winter woes and retain water for our bodies. The outer layer of the skin, the epidermis...

Inflammation may contribute to the persistence of C. diff infection, shows study A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile ( C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and providing nutrients that enable C. diff to thrive. C. diff is a bacterium that causes diarrhea, often with severe or even fatal consequences. As part of its growth cycle,...

Autopsies usually point to a cause of death but now a study of brain tissue collected from people who committed suicide may explain an underlying cause of major depression and suicide. The international research group, led by Dr. Michael O. Poulter of Robarts Research Institute at The University of Western Ontario and Dr. Hymie Anisman of the Neuroscience Research Institute at Carleton University, says that proteins that modify DNA directly are more highly expressed in the brains of people who...