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IMAGE: Newly designed beta-barrel proteins fold spontaneously into their intended structures and embed into lipid membranes. How the proteins were created from scratch, and their future potential in the construction of. view more
Credit: Ian Haydon, UW Medicine Institute for Protein Design
In a milestone for biomolecular design, a team of scientists has succeeded in creating new proteins that adopt one of the most complex folds known to molecular biology. These designer proteins were shown in the lab to spontaneously fold into their intended structures and embed into lipid membranes. Reported in the journal
Science, this research opens the door to the construction of custom nanoscale tools for advanced filtration and DNA sequencing.
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IMAGE: The mitoribosome is attached to its membrane adaptor as it synthesises a bioenergetic protein (glow yellow). view more
Credit: Dan W. Nowakowski and Alexey Amunts
Scientists uncover for the first time how the body s energy makers are made using Cryo-Electron Microscopy (cryo-EM) at eBIC within Diamond which is based in Oxfordshire.
A new paper published in
Science today (19 February 2021) by an international team of researchers reports an insight into the molecular mechanism of membrane-tethered protein synthesis in mitochondria. This is a fundamental new understanding of how the human mitoribosome functions and could explain how it is affected by mutations and deregulation that lead to disorders such as deafness and diseases including cancer development.
After nearly a decade of research, a new test that detects the magnetic properties of malaria-infected blood could soon be used to help eliminate the mosquito-borne disease.
The rare-earth element LAD technology could enable the U.S. to more safely utilize these critical resources from domestic sources and aligned nations, and alleviate dependence on Chinese suppliers and reduce the high-environmental impact solvent-based processes for this $4 billion market.