Launch of a joint call to action by WHO-UNICEF-UNFPA and advocacy brief by PMNCH and partnersFrom 30 November through 12 December, world leaders, experts, and advocates are convening at COP 28 to drive action on climate change. Decisions made in Dubai must be based on evidence and a commitment to meeting the health, rights, and needs of those in vulnerable situations. This panel presents research on the impacts and important actions to protect and promote the health and rights of women, children, adolescents, and future generations: those who will bear the greatest burdens of the climate crisis, and who will be asked to come up with solutions.A growing body of epidemiological evidence links climate hazards to adverse maternal, newborn, and child health outcomes, ranging from gestational hypertension and pre-eclampsia to preterm births, to the development of respiratory diseases and negative effects on learning and family function.Climate change additionally threatens maternal, newborn and child health by disrupting the quality, provision, and use of health services and care practices in the home.The climate crisis is negatively impacting all five domains of adolescents' well-being:Good health and optimum nutrition,Connectedness, positive values, and contribution to society,Safety and supportive environment,Learning, competence, education, skills and employability,Agency and resilience. While there is growing recognition that climate change has health effects, more information is needed about how this happens, who is most at risk and what works to reduce its impact across the life course with a focus on low-and middle-income countries.A deeper understanding of the complex consequences the climate crises have on women, newborns, children, and adolescents, and on sexual reproductive health, rights, and access to services, especially for particularly at-risk populations is critical for developing targeted interventions and policies to reduce the anticipated adverse effects and ensure equitable climate adaptation and mitigation.The intersection of climate change and women’s, children’s, and adolescents’ health is a pressing issue, and urgent action is needed to accelerate progress.AgendaOpening remarks: Dr Maria Neira, Director of Environment, Climate Change and Health, World Health OrganizationKeynote address: H.E. Mitoha Ondo’o Ayekaba, Minister of Health, Equatorial GuineaReflections from Abheet Solomon, UNICEF and Willibald Zeck, UNFPAModerated discussion:Githinji Gitahi, CEO, AMREF Health Africa and Strategic Advocacy Committee Chair, PMNCHMerette Khalil, Founder, Your Egyptian Doula and Knowledge and Evidence Working Group Vice Chair under 30, PMNCHAgnès Soucat, Director of Health and Social Protection, French Development AgencyQ&AClosing remarks: Dr Maria Neira, Director of Environment, Climate Change and Health, World Health Organization Registration