Childrenâs Hospital & Medical Center is also part of the nationwide study. With many more Nebraskans now lining up for first and second shots of COVID-19 vaccines, chatter around who had what side effects â a fever or sore arm versus none at all â have become commonplace. The full list of common, short-term effects includes soreness or swelling at the injection site, fatigue, joint and/or muscle pain, fever and/or chills, headache, nausea and swollen lymph nodes. The good news: Those temporary responses mean your immune system is up and firing, preparing your body to combat coronavirus invaders. The better news: Just because you didnât have much in the way of side effects doesnât mean the vaccine didnât work for you or that you didnât have a strong immune response.