Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency A study of immune-deficient adults and children has shown that patients who fail to respond positively to infections and vaccinations have robust humoral immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) structural proteins. Researchers Hannah Kinoshita et al. described the clinical course, antibody, and T cell responses to SARS-CoV-2 structural proteins in a cohort of adult and pediatric patients with antibody deficiencies (related and unrelated) and infected with SARS-CoV-2. The researchers at Children's National Hospital are the first to demonstrate this response for immunocompromised patients. Their findings are published in the