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Immune dysfunction mechanism discovered in stroke and heart attack patients

Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack.

Germany , Matthias-gunzer , Vikramjeet-singh , Head-of-the-biospectroscopy-department , Institute-of-experimental-immunology , Journal-nature-cardiovascular-research , Leibniz-institute-for-analytical-sciences , Leibniz-institute-for-analytical-sciences-in-dortmund , University-hospital , Leibniz-institute , Analytical-sciences , Journal-nature-cardiovascular

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

Kateryna-kon , Vaccine-development , Npj-vaccines , Reverse-vaccine-development , Antimicrobial-resistance , Accine , Ntibody , Linical-trial , Oronavirus , Fficacy , Iv , Mmunodeficiency

Breakthrough study offers hope for an effective HIV cure

By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic.

United-states , Vietnam , Republic-of , Canada , South-africa , India , Rakai , Uganda , Toronto , Ontario , Ethiopia , American

NIH study uncovers vulnerable sites on Epstein-Barr virus protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

Jeffreyi-cohen , National-institute-of-allergy , National-institutes-of-health , Nih-national-institute-of-allergy , National-institute , Infectious-diseases , National-institutes , Epstein-barr-virus , Irus , Llergy , Ntibodies

Understanding the role played by HIV in pulmonary hypertension

Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year.

Texas , United-states , Ebtesam-islam , Sharilyn-almod , Jeremy-goettel , Igor-ponomarev , Transcriptome-dysregulation , Jacob-nichols , Scott-trasti , Michael-melkus , Duke-appiah , Department-of-immunology

Researchers are using RNA in a new approach to fight HIV

Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year. Now, University of Waterloo pharmacy associate professor Emmanuel Ho has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy. These siRNAs regulate which genes or proteins are turned on or off in ou...

Waterloo , Ontario , Canada , University-of-waterloo , Press-release-image , Society , Earned , Alue , Rna , Ovid-19 , Andemic

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year.

Canada , Waterloo , Ontario , University-of-waterloo , Hiv , Utophagy , Ovid-19 , Ene , Ene-therapy , Enes , Enetic

U of M research offers new avenue of hope in the fight against chronic HIV

Published in the Journal of Infectious Diseases Oxford Academic, research led by the University of Minnesota Medical School offers a new avenue of hope in the fight against chronic human immunodeficiency virus (HIV) infection.

United-states , American , Tim-schacker , University-of-minnesota-medical-school , M-medical-school , American-federation , Minnesota-medical , Infectious-diseases-oxford-academic , Minnesota-medical-school , Natural-killer , Hiv , Esearch

Combination therapy shows promise in targeting latent HIV reservoirs

Antiretroviral therapies (ART) stop HIV replication in its tracks, allowing people with HIV to live relatively normal lives.

David-margolis , Catherine-bollard , Cure-center , Unc-school-of-medicine , School-of-medicine , George-washington-university , Cynthia-gay , Sarah-kenan-distinguished-professor , Infectious-diseases , Hiv , Ids , Ntiretroviral

Vaccines safe for pregnant women with HIV but show reduced immune response

A meta-analysis in eClinicalMedicine finds vaccines are safe for pregnant women living with HIV, showing reduced immunogenicity compared to those without HIV but no increase in adverse events, highlighting the need for their inclusion in vaccine trials.

Ottawa , Ontario , Canada , Virtual-health-library , World-health-organization , Image-credit , Hit-stop-media , Preferred-reporting-items , Systematic-reviews , Newcastle-ottawa-scale , Hiv